Vascular dementia (VaD) is defined as the loss of cognitive functions to a degree that interferes with activities of daily routine life, resulting from ischemic or hemorrhagic cerebrovascular disease or from cardiovascular or circulatory disturbances that injure brain regions that are important for memory, cognition, and behavior (1). VaD is the second most common form of dementia after AD, accounting for approximately 20% of dementia cases worldwide (6). Globally, VaD is more common in men, especially before age 75, whereas AD predominates in women. It is a disease with a progressive course of cognitive impairments resulting due to reduction in blood flow to the brain. In aging demented patients, cerebrovascular alterations are found induced
