The human body must maintain homeostasis for it to work properly. The integumentary and skeletal systems are two of the bodies systems that must work together to maintain homeostasis. When the body cannot maintain homeostasis, many different problems can occur. Osteoporosis is one such problem that can occur when homeostasis is no longer maintained.…
In intramembranous ossification, the bone grows within a membrane. In endochondral ossification,…
Bone forms outside the skeleton, regulating movement. The process of Fibrodysplasia Ossificans Progressiva usually becomes noticeable in the early stages of childhood. The process usually starts with the upper neck and works its way down the body, and into the limbs. Fibrodysplasia Ossificans Progressiva is caused by a mutation in the ACVR1 gene. This gene provides directions for constructing a part of a protein group called bone morphogenetic protein.…
Osteolysis, also known as “disappearing bone disease,” is a condition where parts of your skeleton begin to disappear and is usually a side effect of another underlying cause taking place in your body. Osteolysis tends to be idiopathic which means it came about spontaneously and the cause is undiscovered. The first case of Osteolysis was reported in 1838 in which an 18 year old man’s humerus disappeared completely. It disappeared over a course of 11 years, in which he suffered two fractures to the bone. The man was still able to perform life sustaining activities up until his death at age 70.…
Allows bone to growth in thickness, protects the bone, assists in fracture repair, nourishes bone, and its attachment point for…
Usually the bone loses density, which measures the amount of calcium and minerals in the bone. (Porth, 2011). This disease occurs most often in the elderly, and is seen more commonly among white women. The cause of the disease remains unknown, but it suggests that there is an imbalance of bone resorption and formation (Porth, 2011). The resorption exceeds the formation.…
Fibrodysplasia Ossificans Progressiva The human body is a remarkable structure! Physicians and scientists around the world have been fascinated by its intricate systems for centuries. Fibrodysplasia ossificans progressiva, also know as FOP, has been of peculiar interest to those who have happened to stumble upon it. FOP is a condition in which soft tissue permanently transforms into bone over time.…
Bones can also get brittle and fragile and even result in more chronic disease such as osteoporosis. Treatment of the…
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In these advanced stages, the contours become indistinct and the plate-like character will be lost during the remodeling process. In specific lesions only, the small digital impressions become organized and filled by newly built bone formations (Ortner,…
Osteoporosis mean “porous bone” which corresponds to the look of an effected bone. A healthy bone, when viewed under a microscope, looks like a honeycomb but an effected bone has many more spaces and holes within resulting in the weakness of the bone. The gapping holes causes the bone to be less dense due to the loss of bone mass. When you are young your body will produce new bone more rapidly than it will break down old bone, but as you age, this process slows. Your body beings to break down bone more quickly than it produces new bone, resulting in the weakness of bones.…
There are two processes of development of the bone from fertilisation to adulthood and are intramembranous and endochondral ossification. Intramembranous ossification takes place throughout the flat bone of the skull. It is also responsible for developing jaws, clavicles and collar bones. A development starts after mesenchymal cells in the embryonic skeleton collect together and distinguish into osteoblasts, developing an ossification centre. Osteoblasts start to secrete osteoid and are calcified in a couple of days where mineral salts are placed on it so trapping the osteoblasts inside.…
Bones are living tissues that changes constantly so that new bone cells can be made to replace the old ones. This is known as the bone remodeling. Osteoporosis is the effect of disturbance in the bone remodeling. Cells such as osteoblasts are responsible in making the new tissues while osteoclasts are responsible to break down the bone tissues. Both of these cells works simultaneously work together in bone remodeling.…
When osteoporosis has occurs it slowly deteriorate the cortical and trabecular bone making the bone more prone to becoming fractured or broken. This is due to the fact that osteoporosis has an uneven balance of bone regenerating and breaking down. There is more bone breaking down than building up, which affects the bone to heal. In the article Anatomy of Osteoporosis by Isador Lieberman gives information towards the anatomy of osteoporosis and the reasons of how osteoporosis occurs in the human body. He explains about reaching a certain peak in a persons bone mass would affect the bone once there is an uneven balance in the bone’s build up and break down process, explaining why nutrition and exercise are very important to maintain strong bone…
Figure 2.3: The structure of bone (Abedon, 2014) 2.1.2 Mechanical Properties Bones is always considered as man-made engineering materials. Due to its synthesis there have more variation in properties than engineering materials. The factors can include as the location in body, mineral content, disease, age, gender and the amount of water that presence in the human body. The mechanical properties of bone tissues must be considered as very hard and lightweight material. Mechanical behavior of bone can be explained using composite method.…