There are a wide variety of therapeutics options for lymphomas and the election of them is based on the type of lymphoma, the progression of the disease, characteristics of each patient… However, the 3 main therapeutic options are chemotherapy, radiotherapy and immunotherapy. In this part, these and other methods will be analysed.
Surgery
Surgery has not any relevant role in the treatment of lymphomas13, it just have a role on the diagnosis (obtaining of biopsy material) and prognosis. This is cause lymphomas are blood malignancies so them can be in many places and some cancer cells or small tumor can’t be even seen so remove them with surgery is impossible. However, surgery sometimes can be used in splenic or hepatic lymphomas, …show more content…
They are usually given in combination due to some studies reported a high relapse rate if radiotherapy is performed without chemotherapy. There are a big amount of drugs and different types of combinations so here will be analysed the main methods.
Radiotherapy
Radiotherapy involves the application of radiation (high-energy X rays) on the tumoral area5. It is usually given daily during a determined period of time. The purpose is destroy the lymphoma in the area being treated (curative treatment) or, if it’s not possible, to reduce the amount of cancer cells (palliative radiotherapy) (Radiotherapy for lymphoma. Retrieve from: http://www.lymphomas.org.uk/sites/default/files/pdfs/Radiotherapy-for-lymphoma.pdf). Lymphoma cells are especially sensitive to radiation so this treatment is really effective and the dose can be really low in relation with other cancers
It can be given alone but usually is done in combination with chemotherapy, being given after it.
For lymphoma disease, according to Lymphoma Association5, the main ways of application of radiotherapy are …show more content…
With regards to the dose administrated, it is going to depend on so many factors: the type of lymphoma, the location, the extension of the disease, conditions of the patient… The total dose is given in several fractions to ensure the recovery of the healthy cells and to reduce the side effects. In this way it is important to watch out for the dose and try to reduce it while it is still effective as treatment.
Common uses of radiotherapy are:
In Hodgkin Lymphoma in classical Hodgkin lymphoma radiotherapy is almost always used in early stage while the prescription is less common in advanced stages while for relapses it is not a usual choice. In the case of nodular lymphocyte predominant Hodgkin lymphoma it is recommended in early stages as well. It is used after