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Radiotherapy And Therapeutic Dilemma

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In the instances when these tumors are found to be unresectable (pN2-3 or pT4b) on surgical exploration, one is faced with a clinical and therapeutic dilemma. In this situation, chemotherapy and/or radiotherapy are the only treatment that has been shown to improve survival as described previously. However, systemic chemotherapy and radiotherapy may have severe side effects, such as significant hematologic, mucosal toxicit, intestinal obstruction or gastrointestinal bleeding or perforation, or lead to treatment-related

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