egin{table}[H] centering captionof{table}{Characteristics of hyperoxia studies - 1} label{tab:table 3.15} egin{tabularx}{0.99 extwidth}{p{0.21 extwidth} p{0.34 extwidth} p{0.12 extwidth}p{0.12 extwidth}p{0.12 extwidth}} \ hline abularnewline extbf{Author (year)} & extbf{Study design} & extbf{Hypoxia threshold} & extbf{Control}& extbf{Age} \ abularnewline hline abularnewline Smyth (1998)cite{Smyth1998}& Prospective observational cohort & $< 92\% $ & $ge$ $ 92\% $ & $< 5$ yrs\ abularnewline Onyango (1993)cite{Onyango1993}&Prospective observational cohort & $< 90\%$ & $ge$ $ 90\%$ & $< 3$ yrs\ abularnewline Orimadegun (2013)cite{Orimadegun2013}&Prospective cohort & $ le$ $ 90\%$ & $ > 90\%$ & $< 15$ yrs\ abularnewline Orimadegun (2014)cite{Orimadegun2014}&Prospective cohort& $< 90\%$ & $ge $ $ 90\%$& $< 5$ yrs\ abularnewline Chisti (2012)cite{Chisti2012}&Prospective cohort & $< 90\%$ & $ ge 90\%$ & $< 5$ yrs \ abularnewline Chisti (2013)cite{Chisti2013}&Prospective case-control (unmatched) & $< 90\%$ & $ge$ $ 90\%$ & $< 5$ yrs\ abularnewline Pigula (1993)[37]&Prospective cohort & $PaO_{2} < 60 $ mmHg & $> 60$ mmHg & $< 17$ yrs\ abularnewline hline
egin{table}[H] centering captionof{table}{Characteristics of hyperoxia studies - 1} label{tab:table 3.15} egin{tabularx}{0.99 extwidth}{p{0.21 extwidth} p{0.34 extwidth} p{0.12 extwidth}p{0.12 extwidth}p{0.12 extwidth}} \ hline abularnewline extbf{Author (year)} & extbf{Study design} & extbf{Hypoxia threshold} & extbf{Control}& extbf{Age} \ abularnewline hline abularnewline Smyth (1998)cite{Smyth1998}& Prospective observational cohort & $< 92\% $ & $ge$ $ 92\% $ & $< 5$ yrs\ abularnewline Onyango (1993)cite{Onyango1993}&Prospective observational cohort & $< 90\%$ & $ge$ $ 90\%$ & $< 3$ yrs\ abularnewline Orimadegun (2013)cite{Orimadegun2013}&Prospective cohort & $ le$ $ 90\%$ & $ > 90\%$ & $< 15$ yrs\ abularnewline Orimadegun (2014)cite{Orimadegun2014}&Prospective cohort& $< 90\%$ & $ge $ $ 90\%$& $< 5$ yrs\ abularnewline Chisti (2012)cite{Chisti2012}&Prospective cohort & $< 90\%$ & $ ge 90\%$ & $< 5$ yrs \ abularnewline Chisti (2013)cite{Chisti2013}&Prospective case-control (unmatched) & $< 90\%$ & $ge$ $ 90\%$ & $< 5$ yrs\ abularnewline Pigula (1993)[37]&Prospective cohort & $PaO_{2} < 60 $ mmHg & $> 60$ mmHg & $< 17$ yrs\ abularnewline hline