Pulmonary Exacerbation

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Because water and salt can’t flow freely into or out of cells, the inside of the airways of a person with CF is not as moist as the inside of the airways of a person who does not have CF. This makes it difficult for the cilia to sway freely and sweep the mucus from the lungs.

This causes mucus and germs to build up in the lungs. Germs (which can lead to infection) can then build up in the lungs. This causes inflammation and scarring that can lead to more obstruction. This can lead to pulmonary exacerbations. Pulmonary exacerbations are periods when symptoms get worse. This can mean decreased lung function, as well as more coughing and mucus, infection, and weight loss. Pulmonary exacerbations can also lead to the need for intravenous (IV)

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