Prostaglandins Research Paper

Prostaglandins are known to be key in the initiation of inflammatory response. Their biosynthesis is significantly increased in inflamed tissue. Individual prostaglandins during the acute inflammatory response are well known.

Prostaglandins are lipid autacoids derived from the arachidonic acid. They both mediate mechanisms like the inflammatory response. They are generated from arachidonate by the action of cyclooxygenase isoenzymes and their biosynthesis is blocked by nonsteroidal anti-inflammatory drugs. Prostaglandins may function in both the promotion and resolution of inflammation.

There are four main prostaglandins: prostaglandin, E2, prostacyclin, prostaglandin D2, and prostaglandin F2α. These prostaglandins are uniquely produced