Prometaphase And Metaphase

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The chromatin fibers condensed into chromosomes. As the nuclei disappears, each chromosomes are duplicated as two sister chromatids joined by centromeres. Mitotic spindles are formed in the cytoplasm by centrosomes and microtubules during prophase. During prometaphase, the mitotic spindles move apart and the kinetochores form at the centromeres. Some microtubules are attached to kinetochores and move chromosomes. During metaphase, mitotic spindles move to the opposite poles. Then the chromosomes are pulled by the kinetochore microtubules at the metaphase plate. Sister chromatids are still attach to the kinetochore microtubules. In anaphase, two sister chromatids are separated, and become full-fledged chromosomes. The separated daughter chromosomes

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