Prion diseases are a problematic for the central nervous system. Prions are infectious pathogens that cause fatal neurodegenerative diseases such as Alzaimers and Parkinson disease, Creutzfeldt - Jakob disease (CJD), Fatal Familial Insomnia (FFI), Kuru and Scrapie, among others. The most frequent way to acquire any prions disease is by dietary or inheritances. At the moment, doctors and researchers have not found an effective cure or treatment for these diseases. Understanding the mechanism of how PrPC unfolds and refolds into PrPSc will be a great step forward to the studies of degenerative illnesses. Even though there are articles that offers hints about the structural biology of prions, there still more to discover and understand.
