Principle Of Green Chemistry

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Green chemistry principles were applied to multi-step synthesis reactions; these reactions included the bromination of trans-diphenylethylene, bromination of ethyl trans-cinnamate, and debromination of 1, 2-dibromo-1, 2-diphenylethane. These reactions featured a reflux set-up, which allowed the reactions to occur at higher temperatures and aided in the prevention of the evaporation of the solvent and the loss of product thereby increasing the efficiency of the reactions. Furthermore, the reactions were conducted in accordance to the principles of green chemistry. These principles are utilized to design synthesis processes which minimize the production of malignant compounds that can cause accidents in the laboratory.1 The products collected …show more content…
Hydrogen peroxide and hydrobromic acid are also utilized to generate bromine in situ through an oxidation reaction, and thus this process provides a safer alternative to bromine. As a result, potential accidents in the lab and pollution are minimized; these advantages are associated with two additional principles of green chemistry.1 Additionally, the use of bromine in the halogenation reaction, in comparison to chlorine, also promotes a green reaction because bromination is more selective than chlorination and, as a result, other potential by-products are reduced. However, other metrics of green chemistry are accompanied with tradeoffs. Although there are hazards to consider with their utilization in the laboratory, the use of hydrogen peroxide and hydrobromic acid is more beneficial than using the traditional reagents and solvents of bromination and debromination reactions. Furthermore, water is produced as a by-product of the oxidation reaction; however, water is nontoxic. Through these procedural revisions, the processes of bromination and debromination could potentially be more sustainable and efficient than current, standard laboratory …show more content…
Therefore, it is crucial to understand the effects of utilizing green chemistry principles and how the efficiency of a reaction can be assessed. Hence, the efficiency of the bromination and debromination reactions performed will be presented based on the analyses conducted on the collected products including melting range, TLC, IR, GC-MS and NMR; these procedures are used to assess the purity and identity of the products obtained from each reaction. Furthermore, green chemistry calculations including those for percent yield, atom economy, and E product will be presented which determines the efficiency of the bromination and debromination

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