Pre-eclampsia is a broad term used to define all forms of hypertensive complications in pregnancies. There are quite a number of theories explaining pre-eclampsia. Some of such theories are abnormal blood vessel circulation and tone by abnormal physiologic changes that occur during pregnancy such as cardiovascular maladjustment to pregnancy, altered biology of the placenta, systemic inflammatory response and antioxidants. In this literature review, some pathophysiology resulting in some effects to the mother and foetus, a maker for detecting pre-eclampsia will be considered. Pre-eclampsia, if not managed, progresses to Eclampsia which is the cause of most pre term birth and foetal morbidity. It affects about 2-8% of all pregnancies.
1.0.0 INTRODUCTION
Preeclampsia is one of the most common hypertensive complications …show more content…
Pregnancy features a number of physiological changes to help foetal adaptation and its pathological state results in pregnancy complications. Unlike other hypertensive disorders of pregnancies, preeclampsia is a multisystem disease affecting kidney and liver function and the cardiovascular system attributed to vasospasm and vascular endothelial activation. The incidence of preeclampsia usually occurs in the late 2nd or 3rd trimesters of pregnancy.
These characteristics make the mother and foetus prone to risks such as premature labour with its associated congenital disorders for the foetus Also, compared with normotensive pregnancies, women who are hypertensive during pregnancy or having preeclampsia are at higher risks profile of cardiovascular events and disease (CVD), and other diseases in later years. Pre-eclampsia, if not managed, progresses to a life-threatening condition, Eclampsia, with the onset of seizures.
2.1.0 Physiological changes in normal
1.0.0 INTRODUCTION
Preeclampsia is one of the most common hypertensive complications …show more content…
Pregnancy features a number of physiological changes to help foetal adaptation and its pathological state results in pregnancy complications. Unlike other hypertensive disorders of pregnancies, preeclampsia is a multisystem disease affecting kidney and liver function and the cardiovascular system attributed to vasospasm and vascular endothelial activation. The incidence of preeclampsia usually occurs in the late 2nd or 3rd trimesters of pregnancy.
These characteristics make the mother and foetus prone to risks such as premature labour with its associated congenital disorders for the foetus Also, compared with normotensive pregnancies, women who are hypertensive during pregnancy or having preeclampsia are at higher risks profile of cardiovascular events and disease (CVD), and other diseases in later years. Pre-eclampsia, if not managed, progresses to a life-threatening condition, Eclampsia, with the onset of seizures.
2.1.0 Physiological changes in normal