Abstract:
Polyarteritis nodosa (PAN) is a disease of unknown origin that affects the medium and small arteries of any organ. Isolated polyarteritis nodosa is a rare condition that may be triggered by local exposure to certain agents capable of provoking local immune stimulation without a systemic immune reaction. Symptomatic PAN confined to the testis is extremely rare. We report a case of isolated testicular PAN in hepatitis B infection with chronic unilateral testicular pain and successfully treated by interferon α, systemic steroid and cyclophosphamide for 7 month.
Background:
Polyarteritis Nodosa (PAN) first described by Kussmaul A and Maier R1 as systemic necrotizing vasculitis of small and medium sized muscular arteries that can affect skin, joint, heart, kidney, gastrointestinal tract, and nervous …show more content…
He had previously visited the emergency department several times over the past several months and was treated for medical conditions ranging from groin strain and epididymo-orchitis to testicular torsion. No other significant past medical and surgical history, no allergies, recent travel, alcohol abuse or tobacco use. He was taking treatment for HBV infection and over the counter vitamin supplement. He was the father of one child with no history of sexual transmitted disease. During his this visit to the Emergency Department, patient also had a significant history of constitutional features of low grade fever and weight loss and admitted for further workup. One examination, he was tachycardiac with heart rate of 107, blood pressure 132/84, temperature 37.2 and respiratory rate of 18 with no localized and generalized lymphadenopathy. On genital examination no swelling was seen, but right testis was tender to touch and with no change in pain intensity on raising the right
Polyarteritis nodosa (PAN) is a disease of unknown origin that affects the medium and small arteries of any organ. Isolated polyarteritis nodosa is a rare condition that may be triggered by local exposure to certain agents capable of provoking local immune stimulation without a systemic immune reaction. Symptomatic PAN confined to the testis is extremely rare. We report a case of isolated testicular PAN in hepatitis B infection with chronic unilateral testicular pain and successfully treated by interferon α, systemic steroid and cyclophosphamide for 7 month.
Background:
Polyarteritis Nodosa (PAN) first described by Kussmaul A and Maier R1 as systemic necrotizing vasculitis of small and medium sized muscular arteries that can affect skin, joint, heart, kidney, gastrointestinal tract, and nervous …show more content…
He had previously visited the emergency department several times over the past several months and was treated for medical conditions ranging from groin strain and epididymo-orchitis to testicular torsion. No other significant past medical and surgical history, no allergies, recent travel, alcohol abuse or tobacco use. He was taking treatment for HBV infection and over the counter vitamin supplement. He was the father of one child with no history of sexual transmitted disease. During his this visit to the Emergency Department, patient also had a significant history of constitutional features of low grade fever and weight loss and admitted for further workup. One examination, he was tachycardiac with heart rate of 107, blood pressure 132/84, temperature 37.2 and respiratory rate of 18 with no localized and generalized lymphadenopathy. On genital examination no swelling was seen, but right testis was tender to touch and with no change in pain intensity on raising the right