Pivh Research Paper

Preterm birth (<37weeks gestation) accounts for about 12% of all live-births in the US.1 Although more premature infants may be surviving due to improved obstetrics and neonatal care, they can suffer from complications including peri-intraventricular hemorrhage (PIVH). PIVH arise from destruction of the highly vascular neural and glial precursor cells in the germinal matrix leading to hemorrhage into the ventricular system. The incidence of PIVH among infants with birth weight of less than 1500g is 15-20%2,3 rising to approximately 50% in those with birthweight less than 750g. PIVH predisposes affected infants to lifelong neurological sequels such as cognitive impairment, neurodevelopmental delay and ventriculomegaly.4,5
Ventriculomegaly after