PhysioEx 9 Ex. 11 review sheet Essay

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physioex 9.0
Review Sheet
Exercise 4
Endocrine System Physiology
Name: Kelly E. Fischer Lab Time/Date: 7:00 PM/Wednesday
Activity 1 Metabolism and Thyroid Hormone
Part 1
1 Which rat had the fastest basal metabolic rate (BMR)?
The normal rat had the faster basal metabolic rate, because it was not missing its pituitary gland or its thyroid gland.
2 Why did the metabolic rates differ between the normal rat and the surgically altered rats? How well did the results compare with your prediction?
The normal rat has the highest BMR because it has the glands required to stimulate and regulate the release of thyroid hormones.
3 If an animal has been thyroidectomized, what hormone(s) would be missing in its blood?
Triiodothyronine
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The effect of TSH was to increase the normal rat's BMR
9 What was the effect of TSH injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Why was this effect observed?
There was no effect on the thyroidectomized rat's BMR with the injection of TSH because there was no thyroid gland to stimulate.
10 What was the effect of TSH injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of TSH in the syringe too large, too small, or just right?
The hypophysectomized rat's BMR increased with TSH. The BMR was just below the normal rat's BMR but still lower. The syringe amount was a little too low.
Part 4
1. What was the effect of propylthiouracil (PTU) injections on the normal rat’s BMR? Why did this rat develop a palpable goiter?
The effect of PTU injections on the normal rat was to decrease the BMR. The palpable goiter was due to buildup of the precursors of thyroxine.
2. What was the effect of PTU injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Why was this effect observed?
The effect of PTU injections on the thyroidectomized rat was not visible because there was no thyroid gland to be affected.
3. What was the effect of PTU injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Why was this effect observed?
The

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