Personalized Medicine
In recent years, the growth and changes in medicine has been exponential than linear. With the innovations of new cutting edge technologies, medicine is not only changing through technological perspective but through human perspective as well. While millions of lives have been saved with the traditional one –size-fits-all blockbuster medicine, some drawbacks are still preventing an effective treatment for each individual. An individual’s response to any medications are influenced by many socio-biological factors such as age, weight, medical history, daily lifestyle but it is also affected by their genetic makeup. Medications prescribed on the basis of one’s genetic information are effectual, efficient and practical and …show more content…
Taking this consideration into an account, ‘Personalized Medicine’ has been proposed which use pharmacogenomics that administer correct amount of doses on the basis of an individual genetic makeup. According to FDA, Personalized Medicine is described as “the right patient with the right drug at the right dose at the right time. It is the tailoring of medical treatment to the individual characteristics, needs, and preferences of a patient during all stages of care, including prevention, diagnosis, treatment, and follow-up”. This new way of tailoring medicine would help in study, identification, analysis and diagnosis of any disease caused due to certain mutations in patient’s gene and treatment would be done accordingly to target that specific mutation. The proliferation of bioinformatics and computational genomics plays a pivotal role in making this incentive effective. From extracting the raw data of DNA to understanding the genetic variations and clinical indication of these information, bioinformatics is leveraging these implications towards creating the personalized …show more content…
It has a vast and rich database that contains current and archived genome assemblies of many organisms. The browser tool allows zoom in and look in detail of each chromosomes with detail annotation. The gene sortor tool allows to look for gene expression and homology. The BLAT tool allows in sequence alignment directly to desired genome [4]. “The UCSC genome browser provides a visualization interface that renders the genome sequence data as linear sequence at varying levels of granularity and allows the viewer to navigate along the length of the sequence, jump to specific locations in the genome using genomic coordinates, or zoom in and out do varying levels of detail” [2]. The genome browser is an open source where user can view any data from a single base pair to the whole chromosome and manipulate those data according to their area of interest. It uses the common Gateway Interface to provide interactive content to Browser users [4]. The UCSC genome browser contains variety of analysis tools to help in data mining of big genomic data available in its browser database, fast sequence alignment, display of all chromosomes at once and the results of genome-wide association studies
In recent years, the growth and changes in medicine has been exponential than linear. With the innovations of new cutting edge technologies, medicine is not only changing through technological perspective but through human perspective as well. While millions of lives have been saved with the traditional one –size-fits-all blockbuster medicine, some drawbacks are still preventing an effective treatment for each individual. An individual’s response to any medications are influenced by many socio-biological factors such as age, weight, medical history, daily lifestyle but it is also affected by their genetic makeup. Medications prescribed on the basis of one’s genetic information are effectual, efficient and practical and …show more content…
Taking this consideration into an account, ‘Personalized Medicine’ has been proposed which use pharmacogenomics that administer correct amount of doses on the basis of an individual genetic makeup. According to FDA, Personalized Medicine is described as “the right patient with the right drug at the right dose at the right time. It is the tailoring of medical treatment to the individual characteristics, needs, and preferences of a patient during all stages of care, including prevention, diagnosis, treatment, and follow-up”. This new way of tailoring medicine would help in study, identification, analysis and diagnosis of any disease caused due to certain mutations in patient’s gene and treatment would be done accordingly to target that specific mutation. The proliferation of bioinformatics and computational genomics plays a pivotal role in making this incentive effective. From extracting the raw data of DNA to understanding the genetic variations and clinical indication of these information, bioinformatics is leveraging these implications towards creating the personalized …show more content…
It has a vast and rich database that contains current and archived genome assemblies of many organisms. The browser tool allows zoom in and look in detail of each chromosomes with detail annotation. The gene sortor tool allows to look for gene expression and homology. The BLAT tool allows in sequence alignment directly to desired genome [4]. “The UCSC genome browser provides a visualization interface that renders the genome sequence data as linear sequence at varying levels of granularity and allows the viewer to navigate along the length of the sequence, jump to specific locations in the genome using genomic coordinates, or zoom in and out do varying levels of detail” [2]. The genome browser is an open source where user can view any data from a single base pair to the whole chromosome and manipulate those data according to their area of interest. It uses the common Gateway Interface to provide interactive content to Browser users [4]. The UCSC genome browser contains variety of analysis tools to help in data mining of big genomic data available in its browser database, fast sequence alignment, display of all chromosomes at once and the results of genome-wide association studies