In our brains we have two major areas that are responsible for controlling our movements, these areas are the substantia nigra pars compacta and the basal ganglia. The substantia nigra pars compacta is responsible for producing dopamine, which controls the transmission of messages that initiate and control movement and balance. The basal ganglion is composed of numerous subcortical nuclei, which are crucial for controlling fine motor movements. Unfortunately, these areas of the brain are majorly impacted on people with Parkinson’s disease. These individuals are commonly between the ages of 50 to 65 years old and are estimated to live to about 75 years old. Parkinson’s disease is a slowly progressive, incurable neurodegenerative disorders
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Also, they also have the option to have a surgical procedure that can be done, however, only certain patient can be qualified based on their age and health conditions. The most effective medications prescribed to patient are Levodopa, dopa¬mine agonists, COMT inhibitors, and MAO-B inhibitors. Levodopa and dopa¬mine agonists are most common used medications for patients withs Parkinson’s disease. Levodopa is typically combined with carbidopa, together the both convert into dopamine in order to replace the dopamine that has been lost. Dopamine agonists acts a form of dopamine in order to stimulate never cells. COMT inhibitors and MAO-B inhibitors are used to block any enzymes that break down …show more content…
Neural transplants surgery is completed by placing a placing a fetal donor dopamine producing cells in the basal ganglia. Deep brain stimulation surgery implant a stimulator and electrodes inside the brain. Once the implant is completed, the stimulator and electrodes work cohesively together in order targets the sub-thalamic nucleus or the globus pallidus interna in the thalamus. Sub-thalamic nucleus DBS increase speed of movement, rigidity gait, postural stability, and decrease dosage use of medications. However, it is only effective for patients who are young and healthy. Globus pallidus interna DBS decease dyskinesia and is only appropriate for older patients. Other forms of surgery that can be done are thalamus and pallidotomy surgery, which destroy a small area of the thalamus or globus pallidus to control tremor or
Also, they also have the option to have a surgical procedure that can be done, however, only certain patient can be qualified based on their age and health conditions. The most effective medications prescribed to patient are Levodopa, dopa¬mine agonists, COMT inhibitors, and MAO-B inhibitors. Levodopa and dopa¬mine agonists are most common used medications for patients withs Parkinson’s disease. Levodopa is typically combined with carbidopa, together the both convert into dopamine in order to replace the dopamine that has been lost. Dopamine agonists acts a form of dopamine in order to stimulate never cells. COMT inhibitors and MAO-B inhibitors are used to block any enzymes that break down …show more content…
Neural transplants surgery is completed by placing a placing a fetal donor dopamine producing cells in the basal ganglia. Deep brain stimulation surgery implant a stimulator and electrodes inside the brain. Once the implant is completed, the stimulator and electrodes work cohesively together in order targets the sub-thalamic nucleus or the globus pallidus interna in the thalamus. Sub-thalamic nucleus DBS increase speed of movement, rigidity gait, postural stability, and decrease dosage use of medications. However, it is only effective for patients who are young and healthy. Globus pallidus interna DBS decease dyskinesia and is only appropriate for older patients. Other forms of surgery that can be done are thalamus and pallidotomy surgery, which destroy a small area of the thalamus or globus pallidus to control tremor or