Applicability. The components from the randomized control trial that were incorporated into the PICO question included the population of infants scheduled for routine immunizations and the use of sucrose.
Administration of 2 mL of a 24% oral sucrose solution two minutes before three serial routine immunizations showed effective in decreasing behavioral pain response 5 minutes after treatment administration and shortening the time before returning to a near normal state compared to a sterile-water placebo in infants at two and four months of age. Two minutes following solution administration, both the sucrose group and the sterile-water group reached a maximum pain response with a mean score of 4.54 and 4.39 respectively. Three minutes later …show more content…
Sucrose is medically ideal due to its availability, low cost, easy administrations, rapid acting and non-sedating effects. In addition, the administration of sucrose does not require specialized training for the provider. This means that the infant does not need extensive monitoring and the infant is not exposed to risks that are greater than those associated with daily feedings. According to Hatfield (2008), “this study seems to indicate that a weight-based volume dose of 0.6 mL/kg of a 24 g/1000 mL (24%) oral sucrose solution administered as a preprocedural analgesic prior to three serial routine immunizations is prompt, safe and effective in decreasing behavioral pain response following immunizations in infants” (p.224). The target population of this study was equivalent to that of the PICO question. This study specifically addressed the effects of oral sucrose in the infant population who were receiving routine immunizations. The question of whether or not, oral sucrose decreases infant’s pain for routine immunizations, was statistically proven
Administration of 2 mL of a 24% oral sucrose solution two minutes before three serial routine immunizations showed effective in decreasing behavioral pain response 5 minutes after treatment administration and shortening the time before returning to a near normal state compared to a sterile-water placebo in infants at two and four months of age. Two minutes following solution administration, both the sucrose group and the sterile-water group reached a maximum pain response with a mean score of 4.54 and 4.39 respectively. Three minutes later …show more content…
Sucrose is medically ideal due to its availability, low cost, easy administrations, rapid acting and non-sedating effects. In addition, the administration of sucrose does not require specialized training for the provider. This means that the infant does not need extensive monitoring and the infant is not exposed to risks that are greater than those associated with daily feedings. According to Hatfield (2008), “this study seems to indicate that a weight-based volume dose of 0.6 mL/kg of a 24 g/1000 mL (24%) oral sucrose solution administered as a preprocedural analgesic prior to three serial routine immunizations is prompt, safe and effective in decreasing behavioral pain response following immunizations in infants” (p.224). The target population of this study was equivalent to that of the PICO question. This study specifically addressed the effects of oral sucrose in the infant population who were receiving routine immunizations. The question of whether or not, oral sucrose decreases infant’s pain for routine immunizations, was statistically proven