P 53 also known as “the guardian of the genome” is a tumor suppressor gene that works regulating the cell cycle and apoptosis. It is a very important gene since the lack of its action can allow the cells to divide an abnormal number of times and if action is not taken by the cell’s checkpoints, this could lead to cancer. The evolution of tumors associated with mutations in the p53 gremlin is not well understood and numerous researches have been completed trying to identify all of its characteristics.
As all inherited gene mutations, p53 mutations are present in all somatic cells, but the effect of these mutations can have malignant effect on the cells. Most of these malignant transformations are specific to specific organs. For example, breast
As all inherited gene mutations, p53 mutations are present in all somatic cells, but the effect of these mutations can have malignant effect on the cells. Most of these malignant transformations are specific to specific organs. For example, breast