Ovarian Cancer Assignment

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CANCER RESEARCH ASSIGNMENT
OVARIAN CANCER
SECTION A
Ovarian cancer grows in the cells which make up the ovaries; the ovary, fallopian tube, and uterus. These cells are part of the female reproductive system, and are essential in the fertilization of eggs to create a fetus (Ovarian Cancer Alliance, 2014). Cancer is caused by abnormal cells which grow and spread rapidly to other areas of the body through the bloodstream (metastasis). These cells can form a tumor and follow the process of angiogenesis which is the encouragement of new blood vessels to grow inside the tumor (Cancer Research UK, 2014). 20,000 women are diagnosed yearly with ovarian cancer and 14,000 of which will die. The chance of being diagnosed with ovarian cancer is 1/72 and ovarian cancer is the 5th most common cancer in women. (Kimberley Holland, 2014).
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Epithelial cancers form on the outer layer of bodily organs (epithelium), this is the most common ovarian cancer making up 90% of diagnoses and most are benign. Germ cell tumours are benign and form in the cell that make the eggs, this is a rare form of ovarian cancer making up 3% of all cases (Cancer Research UK, -). Stromal (Sex-cord) account for around 5% of ovarian cancers and form in the ovary cells that release hormones, this tumour is malignant. (Ovarian Cancer, 2016). Ovarian cancer has been linked to the BRCA1 gene and BRCA2, however, this is very rare, only affecting 1% of the female population. The BRCA1 and BRCA2 gene are the only genes connected to ovarian cancer, however there are other causes. (Berry. Parmigiani. Sanchez,

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