The two critical needs in treatment to treat osteosarcoma is to prevent relapse into osteosarcoma and better treatments after surgery. Current treatments in osteosarcoma involve surgery, chemotherapy and radiation therapy. However, the chances of cancer relapses are extremely high. Thus, we need more efficient post-surgery treatments to prevent relapsing of a much stronger cancer. Several new drugs for chemotherapy are being tested to provide better results but none of the drug alone has shown any promising results. However, Sorafenib and everolimus have been tested to use as a treatment if the chemotherapy is given after surgery had failed to prevent relapses of osteosarcoma. Even though this treatment has not reached the 50% Progression Free
