Osteomyelitis Essay

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Osteomyelitis is an infection and inflammation of the bone and bone marrow. It can involve any bone of the human body and can occur through a variety of mechanisms. According to Eid and Berbari (2012) “Osteomyelitis can be acute or chronic and may result from hematogenous seeding of the bone, extension of the infection from adjacent soft tissue, or direct inoculation of the bone through skin and soft tissue defects following trauma or surgery” (p. 51), such as joint replacement or internal fixation of fractures. Osteomyelitis, once established, results into the formation of sequestra by progressive softening and necrosis of the bone. Surgical debridement becomes a requirement for cure at this stage of the disease. Failure is not uncommon despite …show more content…
“The extension of this exudate into the cortex will eventually lead to periosteal elevation or rapture, disrupting the blood flow and causing bone infarction and the formation of an abscess or sequestrum” (Eid and Berbari, 2012, p. 52). In chronic osteomyelitis, little or no ischemic necrosis occurs and the inflammation is mild to moderate. It’s largely determined the type and site of osteomyelitis by the virulence of the infecting organism, the mechanism of the infection, and the immune status and comorbid conditions of the patient. Osteomyelitis could develop through extension of the bone from a remote source of infection, hematogenous seeding of the bone from a remote source of infection, or directly via inoculation of the bone following surgery or trauma. Patients should be suspected with osteomyelitis when swelling, erythema, pain or warmth of the skin and soft tissue overlying bone is present. The only manifestation is commonly subacute or chronic pain. Patients with acute osteomyelitis, systemic symptoms are presents, but it is seldom present in patients with chronic

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