In the article, Hormones: Their Effect on the Oral Cavity, it first talks about the cause of periodontal disease. It says that plaque is the primary factor in the development of periodontal disease along with systemic and local factor. In this article, the author explains how different hormones work in our body and how they can cause periodontal disease. For example, the ovaries produce sex hormones that play a role in the female reproductive system. These sex hormones, estrogen and progesterone can be increased through synthetic hormones. When there is a greater amount of hormones in our system they can accumulate in the gingival tissue because the gingiva has receptors for these hormones. Therefore, hormonal levels can cause periodontal disease
