There are two main Office of Management and Budget (OMB) Circulars that govern the different programs of the USDA; A-110 and A-133. OMB Circular A-110 sets coherent regulations for each federal agency to follow regarding the administration of projects sponsored by the federal government (Guide to Research Compliance). OMB Circular A-133, additionally, is a federally required audit of financial institutions and expenditures in compliance with this said OMB circular. This audit covers any program that receives $500 000 or more in federal funding (Guide to Research Compliance).
One program for instance is the Institutional Animal Care and Use Committee (IACUC). In its simplest form, the IACUC basically ensures