PROTEOMICS AND NUTRIGENOMICS
ASSIGNMENT: PUFA AS NUTRACEUTICAL
SUBMITTED TO: DR. SANAULLAH IQBAL
SUBMITTED BY: MAHAM ABID
REGISTRATION NO. : 2014-ND-026
NUTRACEUTICAL
Nutraceutical is referred to a functional food ingredient or a nutrient that possesses therapeutic properties and claim health benefits among people.
CLASSIFICATION BASED ON CHEMICAL NATURE
Nutraceuticals can be divided as follows:
• Isoprenoid derivatives • Phenolic substances • Fatty acids and structural lipids • Carbohydrates and derivatives • Amino acid-based substances • Microbes • Minerals. PUFA AS NUTRACEUTICAL
Polyunsaturated fatty acids (PUFA) are found in both animal and plant sources. They are termed as “Essential” as they cannot be synthesized by our body. It includes omega 3 and omega 6 fatty acids. Omega 3 is good for the heart health while omega 6 helps in lowering blood pressure, reduces risk of diabetes by controlling sugar levels in our body. FAs are one of the most extensively studied for their role as Nutraceutical and how they affect the gene expression. Polyunsaturated fatty acids (PUFAs) target many transcription factors i.e. SREBP- 1c, LXR, and peroxisome proliferator - activated receptors (PPARs). PUFA suppresses lipogenic genes and induce genes involved in FA oxidation to repartition FA from TAG synthesis to oxidation. …show more content…
Alpha Linolinec acid (ALA), an omega 3 fatty acid is converted to eicosapentaenoic acid (EPA) and then to docosahexaenoic acid (DHA). These are then converted to eicosanoids (hormone like compounds), which are involved in various physiological functions including vital organ function and intracellular activity. Good dietary sources include: Fish such as mackerel and salmon, linseed, soy beans, sesame seeds, avocados, rapeseed and some dark leafy green
ASSIGNMENT: PUFA AS NUTRACEUTICAL
SUBMITTED TO: DR. SANAULLAH IQBAL
SUBMITTED BY: MAHAM ABID
REGISTRATION NO. : 2014-ND-026
NUTRACEUTICAL
Nutraceutical is referred to a functional food ingredient or a nutrient that possesses therapeutic properties and claim health benefits among people.
CLASSIFICATION BASED ON CHEMICAL NATURE
Nutraceuticals can be divided as follows:
• Isoprenoid derivatives • Phenolic substances • Fatty acids and structural lipids • Carbohydrates and derivatives • Amino acid-based substances • Microbes • Minerals. PUFA AS NUTRACEUTICAL
Polyunsaturated fatty acids (PUFA) are found in both animal and plant sources. They are termed as “Essential” as they cannot be synthesized by our body. It includes omega 3 and omega 6 fatty acids. Omega 3 is good for the heart health while omega 6 helps in lowering blood pressure, reduces risk of diabetes by controlling sugar levels in our body. FAs are one of the most extensively studied for their role as Nutraceutical and how they affect the gene expression. Polyunsaturated fatty acids (PUFAs) target many transcription factors i.e. SREBP- 1c, LXR, and peroxisome proliferator - activated receptors (PPARs). PUFA suppresses lipogenic genes and induce genes involved in FA oxidation to repartition FA from TAG synthesis to oxidation. …show more content…
Alpha Linolinec acid (ALA), an omega 3 fatty acid is converted to eicosapentaenoic acid (EPA) and then to docosahexaenoic acid (DHA). These are then converted to eicosanoids (hormone like compounds), which are involved in various physiological functions including vital organ function and intracellular activity. Good dietary sources include: Fish such as mackerel and salmon, linseed, soy beans, sesame seeds, avocados, rapeseed and some dark leafy green