Novantrone's Effect On The Brain And Autoimmune Disease

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Multiple Sclerosis (MS) is a disease that impacts the brain and spinal cord (central nervous system). MS impacts the brain and spinal cord because the myelin sheath, which protects nerve fibers, is attacked by the immune system. Nerve fibers over time deteriorate or they become severely damages to the point where it is not reversible. The cause of this disease is not yet known but is classified as an autoimmune disease. It is said that a mix between genetics and environmental factors could be responsible cause of multiple sclerosis. While MS can become known at any age it primarily affects people between 15 years old to 60 years old. If a family member such as a parent of sibling was diagnosed with MS, you are twice as likely to develop this …show more content…
Novantrone is used for relapses in multiple sclerosis. The generic form of Novantrone is Mitoxantrone. Novantrone is given through and IV and must be administer by a healthcare professional. The IV treatment last about five to fifteen minutes and is administered every three months. The recommended dosage strength is 12mh/m2. Side effects include black tarry stools, bladder pain, bloody or cloudy urine, cough or shortness of breath, painful urination, dizziness, fainting, irregular heartbeat, frequent urge to urinate, lower back or side pain, pale skin, stomach pain, swelling or inflammation of mouth, trouble breathing, ulcers in mouth, unusual bleeding or bruising, unusual tiredness or weakness. Contraindications include patients who have prior hypersensitivity to Novantrone. No dietary restrictions have been …show more content…
Avonex is another immunosuppressant, and its mechanism of action is unknown. Avonex is administered intramuscularly and the recommended dose is 30 micrograms once per week. The first week of taking Avonex the dosage is 7.5 micrograms, 15 micrograms on week two, 22.5 micrograms on week three, and then 30 micrograms on week four. Administration should be on the same day each week. The generic form of Avonex is interferon beta-1a. The powder form of Avonex should be mixed with a liquid into a medicine vial and gentle swirled around not shaken. Prefilled syringes or a single use vial is available as well for one use only. Avonex should be stored in a refrigerator, but the prefilled syringes may be taken out of the refrigerator and store at room temperature prior to injection. However, Avonex may be kept at room temperature for short periods of time if it is protected from light. The powder can be stored at room temperature for up to 30 days, and the prefilled syringes can be stored at room temperature for only 7 days. After the powder is mixed it should be stored in the refrigerator and used within 6 hours. Side effects include black tarry stools, chest pain, chills, cough, diarrhea, fever, flu-like symptoms, headache, joint pain, muscle aches, nausea, pain, difficult or painful urination, shortness of breath, ulcers in mouth, swollen glands, unusual bleeding or bruising, and tiredness or weakness. Contraindications for

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