Scientists studying the human intestinal tract have discovered that there are over 35,000 microflora species in the human gut. For nutrient metabolism, GI microflora works to get nutrients from the breakdown and fermentation of carbohydrates, lipids, amino acids, and polyphenols. For xenobiotic and drug metabolism, GI microflora help to aid in therapy of diseases, reduce competitive inhibition in the liver, and induce deconjugation in anticancer drugs. As a gut barrier and structure, GI microflora helps with the maintenance of desmosomes, maintaining tight junctions, decrease metabolic endotoxemia, and by inducing the transcription factor angiogenin-3. In the protection against pathogens, GI microflora work to fight off diseases as they have a symbiotic relationship with the gut bacteria (Jandhyala).
Abnormal gastrointestinal bacteria result when microflora get disturbed from doing their normal functions of fighting infections and diseases. One of the main causes of this is the use …show more content…
When your microflora is decreased in your GI tract, nothing good can come out of it. Good thing there are ways to put some healthy microflora back into your gut to help prevent any of the above diseases to occur within your body. A few examples of how to restore your GI microflora are to eat fermented foods, take probiotic supplements, or to eat lactic acid yeast wafers. By eating fermented foods, you are putting lactic acid back in your gut to help with the digestion of carbohydrates. By eating lactic acid yeast wafers, your body will start to ferment fiber into important acids, which will overall improve your body’s ability to absorb vitamins, minerals, and fat (Dr. David