One cigarette contains approximately 10 milligrams of Nicotine.
Since not all of the fumes go into the persons lungs, each time a person puffs a cigarette, only 1 or 2 milligrams of Nicotine gets into the body. It may not seem like much but in fact, just one drop of pure Nicotine would kill a human being.
The time taken is 7 seconds to reach the brain; which is a very short time. The reason that it does not take long is because there is a chemical in the brain called Acetylcholine that carries messages between individual brain cells. Acetylcholine is responsible for maintaining normal heart function, healthy respiration, movement of muscles and cognitive functions