There are three types of muscles in the human body: cardiac muscle, smooth muscle and skeletal muscle. For the purpose of our lab we will be focusing only on skeletal muscle. Skeletal muscle is the only voluntary muscle tissue found in the human body. They're attached to bones by tendons and are responsible for all the movements that are consciously controlled such as writing, walking, running, etc. [1].…
These muscle fibers are composed of myofibrils, which not only give the muscle its striated appearance but also are also composed of contractile proteins known as actin (thin filaments) and myosin (thick filaments). Each actin protein has a binding site for myosin, which is regulated by two proteins known as Tropomyosin and Troponin. Both of these regulator proteins inhibit the binding of myosin to actin by overlapping the binding sites in a confirmation that could be described as a ribbon (Tropomyosin) and a thumbtack (Troponin). Each skeletal muscle is then divided and encapsulated by three difference layers of connective tissue. The first of these layers enclosed the whole skeletal muscle and is known as the epimysium, the second layer of connective tissue called the perimysium encloses each fascicle and finally the last layer of connective tissue which encapsulates each muscle fiber, which is known as the…
The firing of gamma motor neurons in sync with alpha motor neurons pulls muscle spindles, innervating the muscle. The spindle is innervated by type Ia sensory fiber that goes on to synapse with alpha motor units. Therefore, there are more motor units being put to work and the type 1a afferents maintain their sensitivity.…
2. Length-tension relationship states the amount of the tension generated by the contraction of the muscle will vary on the length of the muscles at rest. The beginning and end of a contraction will be considered a weak-contraction or too stretched which means the myosin is to close to the Z-discs or the myosin overlaps which does not allow a correct cross-bridge to occur. When the contraction is at regular resting length will produce the greatest force when muscles contract.…
INTRODUCTION The proteins actin and myosin is the caused of excitement of skeletal muscle. It can be made chemical, electrical and mechanic. When the muscles are use many times to the maximum force, the muscle will decline. That decline is called muscle fatigue.…
A muscle tear refers to muscle fibers being damage (Virginia 2013). A tear in the gastrocnemius can cause great risk of injury since the gastrocnemius is located between the knee and ankle joint (Virginia 2013). This can be cause by direct trauma to the calf region or sudden landing on the foot (Medial Head Gastrocnemius 2006). This injury is common in tennis players due to the constant motions of jumping and lunging (Medial Head Gastrocnemius 2006). In the first degree of gastrocnemius tear, the individual will experiment pain but the tendon will not be lengthened (Medial Head Gastrocnemius 2006).…
Belgian Blue bulls have extremely large muscles in the shoulder, back, loin and rump area. This extreme growth in muscle is due to a mutation in the myostatin gene, which results in the production of increased number of muscle fibers (hyperplasia). Breeders choose the cattle that clearly demonstrate the myostation defect. They choose the cattle that has the most muscle mass so they can gain the best out of their offspring. By doing so they also eliminate the undesirable characteristics in the species.…
They have higher levels of PPARβ/δ to increase fatigue resistance and act as a transcription factor to promote ‘slow’ genes. Slow twitch muscle fibers also have slow Calcium ATPase and lower activity myosin ATPase, which both work to cause longer contractions. Fast twitch, type II, fibers are the opposite of slow twitch fibers and involve more anaerobic activity. They have fast Calcium ATPase and High activity Myosin ATPase causing shorter, faster contractions. These muscles have three types; IIa, IIb, and IIx/d. Type IIb fibers are fast and glycolytic and while working out fatigue quickly; these are the muscle types that beginners usually have coming into BJJ.…
The muscle strength and reflex lab uses the involvement of two subjects to demonstrate the electrical properties of muscles and their motor neurons. With the relative strength and electrical activity of the dominant forearm, the observed data showed how the dominant forearm will average a higher force due to the amount of strength that arm may or may not have, and the amount of receptors that contract in unison. Supporting our second hypothesis, the non-dominant forearm resulted in a higher fatigue rate than the dominant forearm. This demonstration shows how the dominant arm with larger diameter fibers will be more likely to have more mitochondria and myofibrils causing the longer fibers to fatigue. There may also be a case where the dominant…
Introduction Some people believe that we have only one type of muscle in our bodies that help us with all different types of tasks, however; not only do our bodies have different muscle types, they also contain different muscle fibers that are used for different activities. Skeletal muscle contain three types of muscle fibers: slow twitch, fast twitch oxidative, and fast twitch glycolytic. Most muscles in our bodies have different combinations of these muscle fibers, although our body recruits different muscle fibers for different activities. The first muscle fiber to be recruited are slow twitch fibers, are also known as Type I. “Slow twitch muscle fibers are the smallest in diameter, contain the least amount of actin and myosin, and allow…
Each molecule is described as being “shaped like two golf clubs twisted together” (Tortora and Derrickon, 2011), with the tail facing the M line that appears at the centre of the sarcomere. Actin is thinner and its molecules come together in a twisted helix shape to form the thin filaments that come from the Z disc of the sarcomere. What is important to note here is that every actin molecule has its own myosin binding site. This means that the myosin heads, the “golf club” like structures depicted earlier, can attach themselves to the actin – it is this action that causes muscle contraction as we shall see.…
Muscular dystrophies (MD) are diseases that causes muscle mass loss and weakness (this is normally in children but can happen in adults). This is caused by abnormalities in genes that interfere with proper production of protein to form healthy muscles for voluntary movement. When the brain sends signals to a muscle to contract, it goes through the spinal cord and peripheral nerves to the neuromuscular junction, releasing the chemical acetylcholine that triggers muscle contraction. From here, transportation of the chemicals produced from the reaction of acetylcholine go through muscle fiber membrane and the muscle contracts or relaxes. This membrane has a group of proteins called dytrophin-glycoprotien complex that protects the muscle fiber…
GTOs play an important protective role for the muscle system since they sense changes in muscle tension. Because of this they can protect the muscle from excessive tension by causing the muscle to relax thus prevent injury and damage of muscles. Essay Questions 1. The sliding filament theory is how muscles are able to create force when having the thick (myosin) filaments slide past the thin (actin) filaments during muscle contraction overlapping in ratchet-like manner, this causes the sarcomere to contract, while staying at the same length. Nerve impulse causes the release of Ca+2 enabling the myosin bridges to bind with actin.…
The dystrophin gene is located on chromosome X on the short arm. It contains more than 3685 amino acids. While it only accounts for a little of the proteins, its effects are very important. Duchenne and Becker the cells dies and is invaded by macrophages. Other types are affected by complex proteins outside of the X…