Multiple Sclerosis Essay

2216 Words Oct 1st, 2014 9 Pages
Kneiser 1

Multiple Sclerosis Pathophysiology 216C11 Professor Steggall Bessie Kneiser November 28, 2011

Kneiser 2

Abstract

Multiple Sclerosis is a chronic immune mediated disease that affects the central nervous system.
The bodies immune system attacks normal tissue and/or organs. The attack starts with inflammation against myelin and the cells that make the myelin. Myelin is the insulation that surrounds axons and speeds up nerve impulses. There are multiple symptoms that characterize MS. Double vision, fatigue, numbness and weakness are common traits. Pain in
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Kneiser 3
Bessie Kneiser
Professor Steggall
Patho final paper
November 28th, 2011

Multiple Sclerosis Multiple Sclerosis (MS) is a chronic immune mediated disease that effects the central nervous system (Kalb Questions 7). It is most commonly diagnosed in young adults (7). Worldwide, MS is thought to affect more than two million people (7). The current estimated prevalence of MS in the United States is 350,000 to 400,000 individuals, which means approximately one in 750 people have the diagnosis at any given time (7). There are around 10,000 new cases diagnosed in the United States every year (7). MS is a chronic illness that is not always disabling but can change one's life forever (7). MS is more prevalent in temperate areas of the world (Kalb Questions 7). It is more common in individuals from Great Britain, Scandinavia, and northern Germany (8). It is relatively unusual in tropical areas (8). It is more common in the northern part of the U.S. It is extremely rare among Africans (8). MS appears mostly in people who are genetically predisposed (8). MS is considered an autoimmune disease (Kalb Questions 8). The body's immune system attacks normal tissue and/or organs (8). This attack starts with inflammation against the myelin and the cells that make the myelin (8). This process is called demyelination (9).
Leaks in the blood-brain barrier where immune

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