Multiple Sclerosis Case Study

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Multiple Sclerosis (MS) is an autoimmune condition that is characterised by chronic inflammation, with the target of the immune response being the myelin sheath that surrounds the axons of nerves (1), as well as the oligodendrocytes responsible for producing the myelin (2). The neurodegeneration is largely driven by the over activation of microglia, chronic oxidative injury and mitochondrial damage in the axons of nerves (3). Chronic demyelination of the neurones in the CNS is generally followed by neuronal damage in the grey and white matter of the spinal cord (3), with the end result being irreversible neurological symptoms (1). The myelin sheath is responsible for providing insulation for the electrical impulses (known as the action potential)

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