Multilobular Osteochondrosarcoma Research Paper

Multilobular osteochondrosarcoma (MLO) is a rare malignant tumour of the flat bones of the skull with reports of the tumour occurring at other sites [1]. Similar names used for this tumour type include chondroma rodens, multilobular tumour of bone, multilobular osteosarcoma, multilobular osteoma, calcifying aponeurotic fibroma, multilobular chondroma, cartilage analogue of fibromatosis, and juvenile aponeurotic fibroma. [1]

MLO is a seen primarily in older, medium to large breed dogs. However there have been reports of the tumour occurring in young as well as small breed dogs. The tumour has also been seen in humans, cats and horses. MLO is clinically presented as a well circumscribed, firm and fixed mass. It is a slow growing, locally invasive tumour that can be either malignant or benign. Reports have shown that reoccurrence is high after surgical excision. Metastasis was previously shown to be rare however recent studies shows a more variable metastatic pattern. There is a possibility of neurological signs during clinical presentation. This depends on the location of the tumour as well as the invasiveness of the tumour. However, the tumour typically compresses the brain rather than infiltrate the brain. This often results in the late onset of neurological signs. …show more content…
Complete excision of tumour suitable with margins is the best choice. However, it is a challenge to obtain the necessary surgical margins due to the presence of vital structure, if damaged may cause fatal