Modern scientific studies have revealed the therapeutic functions of insect extractions include antibacterial, anti-inflammatory, antitumor activities, immune regulations and reducing blood sugar. Mulberry silkworm, Bombyx mori L. is to be one of the commercial insects that have high medicinal value and are usually used to reduce blood pressure, diabetes, nerve disorders and heart problems. Nutrition plays an important role in improving the growth and development of silkworm Bombyx mori L. like other organisms (Legay, 1958). In the present study, the antibacterial activity of sericin from sporlac, treated silkworm against five human bacterial pathogens such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes
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Among all the bacterial pathogens tested, maximum activity (17.3±0.6mm zone of inhibition) was found against S.pyogenes at the concentration of 5% and the minimum activity (14.2±0.2mm zone of inhibition) was found against E.coli (Table.1).
Table.1 Antibacterial activity of sericin obtained from silkworm cocoon treated with different concentration of sporlac against human pathogens
Organisms Zone of inhibition in diameter(mm)/concentration of sporlac treated silk worm Untreated 1% 3% 5%
Escherichia coli 8.7 ± 0.2 11.3 ± 0.2 12.3 ± 0.2 14.2 ± 0.2
Pseudomonas aeruginosa 9.6 ± 0.2 12.7±0.2 14.5±0.3 …show more content…
In the present study the antibacterial activity of sericin from sporlac, treated silkworm against five human bacterial pathogens such as E. coli, P.aeruginosa, S. aureus, S. pyogenes and K. pneumonia was investigated by disc diffusion method. Pandiarajan et al. (2011) has investigated the antibacterial activity of cocoon shell extract and proved that the cocoon shell extract inhibited the growth of micro organisms such as E.coli, B. cereus, P. aeruginosa, S. aureus and K. pneumoniae. Jassim and Al-Saree (2010) isolated and identified some pathogenic bacteria like S.aureus, P.aeruginosa, E.coli and tested the antimicrobial activity of sericin against these pathogens and concluded that the protein sericin has good antimicrobial properties. The antibacterial activity of erisericin in the representative gram negative (E.coli) and gram positive (S.aureus) bacteria models were observed by Senakoon et al.
Among all the bacterial pathogens tested, maximum activity (17.3±0.6mm zone of inhibition) was found against S.pyogenes at the concentration of 5% and the minimum activity (14.2±0.2mm zone of inhibition) was found against E.coli (Table.1).
Table.1 Antibacterial activity of sericin obtained from silkworm cocoon treated with different concentration of sporlac against human pathogens
Organisms Zone of inhibition in diameter(mm)/concentration of sporlac treated silk worm Untreated 1% 3% 5%
Escherichia coli 8.7 ± 0.2 11.3 ± 0.2 12.3 ± 0.2 14.2 ± 0.2
Pseudomonas aeruginosa 9.6 ± 0.2 12.7±0.2 14.5±0.3 …show more content…
In the present study the antibacterial activity of sericin from sporlac, treated silkworm against five human bacterial pathogens such as E. coli, P.aeruginosa, S. aureus, S. pyogenes and K. pneumonia was investigated by disc diffusion method. Pandiarajan et al. (2011) has investigated the antibacterial activity of cocoon shell extract and proved that the cocoon shell extract inhibited the growth of micro organisms such as E.coli, B. cereus, P. aeruginosa, S. aureus and K. pneumoniae. Jassim and Al-Saree (2010) isolated and identified some pathogenic bacteria like S.aureus, P.aeruginosa, E.coli and tested the antimicrobial activity of sericin against these pathogens and concluded that the protein sericin has good antimicrobial properties. The antibacterial activity of erisericin in the representative gram negative (E.coli) and gram positive (S.aureus) bacteria models were observed by Senakoon et al.