Just like the cell, the mitochondria have different part. The matrix is the gel like fluid similar to the gel-like fluid cytoplasm. Cristae are the folds in the membrane. The …show more content…
According to the North American Mitochondrial Disease Consortium, mitochondrial disease primarily effects children but recently adult-onset disorder is frequently being recognized. Mitochondria are abundant in nerve, liver, and muscle cell. The neurons for example need proper distribution of mitochondria to satisfy the energy required to maintain an electrical excitability and synaptic transmission. The function of mitochondria in the neurons are need to produce energy, Ca2+ buffering, axonal, and dendritic transport and release and re-uptake of neurotransmitters (Hanu. N.d.). Thus dysfunctional mitochondria can lead to encephalomyopathy or brain and muscle disease. Mutation in the mtDNA are the causes of mitochondria disease. “In the Kearns-Sayre Syndrome (KSS), single, large-scale mtDNA (usually sproaid ) were detected in muscle biopsies, and mitochondrial ultrastructural and cyttochemical abnormalities in the muscle were apparent” ( MT DNA