Wound infection is one of the most common causes of death in modern society, especially in people less than 44 years(Shu Fan et al., 2013). Bacterial microorganisms can gain access from environment or from surrounding skin surface into underlying tissue when patient compromised and physical characteristics are optimal for colonization and growth(Irena Pastar et al., 2013).Presence of microorganism that proliferate without immune response is known as colonization.(Abdul R. Siddiqui and Jack M. Bernstein, 2010). Delay in wound healing characteristic by excessive amount of exudates that affect healthy skin tissue around the wound (Boateng and Catanzano, 2015).
Skin repair is an important physiological process that essential not only for homeostasis and restore barrier function, but also to …show more content…
There are many factors can affect wound healing such as age, smoking, diabetes, venous and arterial insufficiency in addition to the presence of resistance strain of microorganism(Garazi Gainza et al., 2015; Hajighasemali Davooda et al., 2016). Healing process involves interaction between different types of cells such as blood cell, fibroblast, epithelial cell and leukocyte (LeBert and Huttenlocher, 2014). Wound repair consists of four main stages that need to be organised to achieve proper skin tissue and restore protection from any opportunistic microorganisms(Thomas S. Lisse et al., 2016). These stages comprise platelet clot formation to re-established homeostasis, in addition to inflammation, tissue formation and remodeling to restore the internal or external of
Skin repair is an important physiological process that essential not only for homeostasis and restore barrier function, but also to …show more content…
There are many factors can affect wound healing such as age, smoking, diabetes, venous and arterial insufficiency in addition to the presence of resistance strain of microorganism(Garazi Gainza et al., 2015; Hajighasemali Davooda et al., 2016). Healing process involves interaction between different types of cells such as blood cell, fibroblast, epithelial cell and leukocyte (LeBert and Huttenlocher, 2014). Wound repair consists of four main stages that need to be organised to achieve proper skin tissue and restore protection from any opportunistic microorganisms(Thomas S. Lisse et al., 2016). These stages comprise platelet clot formation to re-established homeostasis, in addition to inflammation, tissue formation and remodeling to restore the internal or external of