The airway, which includes the nose, mouth, pharynx, larynx, trachea, bronchi, and bronchioles, carries air between the lungs and the body’s exterior. The nasopharynx serves to remove large particles from inhaled air, add moisture, and moderate the temperature. The tracheal and bronchial tract serves as the conducting airway to the alveoli. The pulmonary acini are the sites were oxygen and carbon dioxide are exchanged between blood and the air, and are the main sites of absorption of toxicants that exist in the form of gases and vapors. (Lu’s Basic Toxicology, …show more content…
Therefore inhalable toxicants can be in the forms of gases, vapors, liquid droplets, and solid particulate matters. Toxicants such as Tetrachloroethylene, depending on the particular size, may either be absorbed or exhaled. And when inhaled, this might exert systemic effects from respiratory tract and distributed it to other tissues which may induce local effects on the respiratory tract or both. There is a possibility the respiratory tract may be affected after exposure from another route. For example, if Tetrachloroethylene is inhaled, and passes through the respiratory tract, thus reaching the blood stream then sent to the liver. Depending the level concentration the immune system. could be effect. (Lu’s Basic Toxicology,