Metformin Case Studies

As identified in the previous studies mentioned by Knowler et al., (2002) and Gilles et al., (2007) metformin has shown to reduce the risk from progression of prediabetes to diabetes. Moin et al., (2002) case-control study looking at causality examined metformin prescription use for diabetes prevention in individuals with identified prediabetes over a three year period in 17,352 working-age adults. Of the total sample size on 3.7% of patients with prediabetes were actually prescribed metformin. Women, obese, or those with two or more comorbid conditions were two times more likely to be prescribed metformin. Conclusively, metformin was rarely prescribed for diabetes prevention in working-age adults despite research showing its effectiveness. Moin et al., (2002) identified the need for additional studies to understand the barriers to prescribing metformin for prediabetes therapy.
As a means to guiding research to …show more content…
The research reviewed echoed the importance of lifestyle interventions in the prevention or delay of type 2 diabetes. The availability to programs geared toward lifestyle interventions should be a top priority for communities as it was shown in several studies that cost-effective, easily accessible programs with detailed group and individualized counseling increased adherence to such interventions thus reducing the risk of diabetes. Questionably, if patients with prediabetes maintained strict lifestyle modification interventions would the research indicating that metformin was more effective be overturned? Continued research would be needed to determine the relevance of this posed question. The health care team and researchers would need to promote programs as described above with continued support in order to determine whether or not strict lifestyle modifications interventions would outweigh metformin use over many