Cancer cells can break away from the primary tumor site and travel through blood and lymphatic vessels. This is how cancer cells spread, or metastasize, to another part of the body, such as the brain. These tumors can develop when a patient’s primary cancer, while still undetectable at its original site, sends out metastatic cells that travel to the brain and establish themselves there. Most cancer patients are actually at risk of having their tumor spread to multiple sites. Metastasis, the process that allows some cancer cells to break off from their tumor of origin and take root in a different tissue, is the most common reason people die from cancer. Metastatic brain tumors are ten times more common than primary brain cancers. Brain metastases are diagnosed in 10 to 40% of all cancer patients. Unfortunately, brain metastases are
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Thus, we are in need of such information and models for development of new, efficient therapies. The essential role of the tumor microenvironment in cancer progression has been well documented for many
Thus, we are in need of such information and models for development of new, efficient therapies. The essential role of the tumor microenvironment in cancer progression has been well documented for many