Metabolic Effects Of Whole Grain Wheat And Whole Grain Rye

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The article “Metabolic effects of whole grain wheat and whole grain rye in the C57BL/6J mouse” is an article that consists of a study that compared long term effects from diets that consisted of whole grain wheat and whole grain rye. The article is a peer reviewed article published by Eleviser Science in the Nutrition journal in February of 2010. The purpose of the study was to test the hypothesis that a whole grain wheat diet causes reduced insulin responses and increased body fat compared to whole grain rye diet. The results of the study became prevalent as certain research showed that whole grain cereals consumed in a low fat diet reduce the likelihood of type 2 diabetes and regulate weight control. The sample size of the study is the …show more content…
The first group contained a sample size of 7 mice that consumed a controlled diet with whole grain wheat diet combined with a low fat diet and the other group was a sample size of 7 mice that consumed a whole grain rye diet combined with a low fat diet. The duration of the study was over the course of 22 weeks. The study includes the type of research such as; Epidemiological and Laboratory-based studies. The scientific testing methods used included the following; oral and intravenous glucose testing, taking blood samples, measuring glucose in the plasma, adipocyte morphometry, lipid extraction from feces and RNA preparation. The quantitative methods used included measuring body weight, measuring food intake from was left in the mouse cage at the end of the week, the spillage of food in the cages and conducting a meal study with a sample of 10 mice. These approaches analyzed the fat and protein contents, available starch and insoluble and soluble dietary fibers in the …show more content…
During weeks 18 and 19 of the study the results showed that the whole grain rye group experienced significant lower body weight as well as decreased body fat content at week 22 compared to the whole grain wheat group. The total insulin was higher in the whole grain wheat group that resulted to higher post-prandial insulin response compared to the whole wheat rye group. The objective of the study was to determine if whole grain cereals prevented obesity and diabetes. The authors concluded that there was no correlation and that whole grain diets will only affect people who are already obese as they will experience a change in their overall weight, but that whole grain rye is better for insulin response than whole grain

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