The pupil dynamics under diverse light circumstances (mesopic and photopic conditions) alters the result of the aberration on the depth of focus. The summary of both positive and negative spherical aberration using adaptive optics technology can significantly shift and increase the patient's overall depth of focus. Due to the waveform shape, negative spherical aberration seems preferably matched to achieve a desired rise of the depth of focus in a presbyopic patient with a pupil that has a strong response to accommodation. Functional and anatomical boundaries may relate when considering the spherical aberration method. The flexibility of the individual's corneal aberrations and the mesopic versus photopic pupil size dynamics might affect clinical
