Merkel-Cell Carcinoma Research Paper

Improved Essays
Merkel-cell carcinoma is a rare type of malignant skin cancer or disease that grows out of control. It most often starts in areas of skin that is being exposed to the sun, especially the head, neck, arms, and legs. This type of skin disease tends to grow quickly and metastasize at an early stage; this most often become more developed in older people. Metastatic Merkel-cell carcinoma is often deadly and there is no effective treatment. Findings made by a physician-researcher of University of Arkansas for Medical Sciences, Ling Gao, M.D., Ph.D., about an existing drug that can exclude the patient’s stage four Merkel-cell carcinoma with a drug called idelalisib.
An 86-year old female patient who was diagnosed with metastatic Merkel-cell carcinoma

Related Documents

  • Improved Essays

    Nivolumab Case Studies

    • 949 Words
    • 4 Pages

    The antitumor effect of nivolumab in the melanoma regiment was followed by another trial with 107 patients, where 31% of the patients had an impartial response, with a median duration for 2 years. Of these responders, 15 responded to the therapy by 8 weeks during the first assessment, 12 had continued responses for minimum of 4 months after ending the therapy, while 17 had responses but left the program unexpectedly. Now, nivolumab use has achieved an improved outcome in patients with melanoma and NSCLC (Mahoney et al. 764-782). Moreover, a Phase III trial was conducted in melanoma, where nivolumab was compared to dacarbazine.…

    • 949 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Ewing’s sarcoma is a type of childhood cancer that is found in children’s around the age of 10 years old. The cancer is the second most common bone cancer and initiates in the large bones of the body. In the eyes of Lucy having cancer at her young age made her feel important. “ …Its promise of rare and dangerous implications made me feel important…” (Grealy, Page 44) Lucy at this stage n her life has no idea of the implications involved in having cancer.…

    • 163 Words
    • 1 Pages
    Improved Essays
  • Decent Essays

    Actinic Keratosis (AK) is a skin disease in which lesions form on the skin due to being over-exposed to ultraviolet light rays. This disease may develop into Squamous Cell Carcinoma (SCC). AK is usually pretty common lesions on the skin that are usually red, brown, or nude colored, rough patches on the skin that has been over-exposed to UV light rays. The more of AK that a person has, the more of a risk the person has of developing melanoma skin cancer. As AK grows and develops, it can become thicker and become larger, and can develop into SCC.…

    • 439 Words
    • 2 Pages
    Decent Essays
  • Decent Essays

    Malignant Melanoma Melanoma is caused mainly from the intense exposure of UV radiation from the sun. Melanoma starts in the epidermis and stratum Basale layers. The UV rays will eventually cause the DNA replications which will make the cells replicate very fast making the cancer tumors. When treated early it is most of the time solved and doesn’t come back. When the early melonoma is not treated it will soon turn into malignant melonoma and will spread around the body to many vital organs.…

    • 697 Words
    • 3 Pages
    Decent Essays
  • Improved Essays

    Malignant melanoma is a form of skin cancer that forms in melanocyte cells in the basal layer of the epidermis which produce melanin that gives human their skin, hair, and eye color. Malignant melanoma grows malignant tumors due to DNA damage to the skin cells probable to UV radiation that causes mutations and sets off skin cells to multiply rapidly and form these malignant tumors. Melanomas are closely similar to moles making it difficult for a person to distinguish from a normal mole to a malignant mole or melanoma. Most melanomas are black or brown in color, but some can also be pink, red, purple, blue, or even white. Melanoma has 5 stages, stage 0 and 1 being localized; stage 0 is noninvasive while stage one has invaded the skin…

    • 985 Words
    • 4 Pages
    Improved Essays
  • Superior Essays

    Cancer, the dreaded six letter word that will affect almost everyone at some point in their life; whether cancer is their cancer or the cancer of a loved one. What happens when the cancer the doctors said was gone comes back only a year later and this time worse than before? For Mary Williams, this just so happened to be her case. Her malignant melanoma is back and this time an unspoken terminal is present in the diagnosis. As a mother of two young girls, eight and eleven years old, Williams is given no choice but to fight.…

    • 1395 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    The Benefits Of Melanoma

    • 818 Words
    • 4 Pages

    Melanoma is a type of cancer that is considered one among the most dangerous. Melanoma traces are usually found over the skin, but rarely it can even be found in the eye or even in the internal organs. The main cause of Melanoma is the direct exposure to the ultraviolent (UV) rays. Reducing tanning from sun or from tanning lamps can curtail the chance from Melanoma. For past decades, recovery from Melanoma was a nightmare.…

    • 818 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Melanoma Research Paper

    • 603 Words
    • 3 Pages

    The American Cancer Society estimates that skin cancer is the most prevalent of all cancers with over 2 million cases of non-melanoma skin cancer each year and 75,000 melanoma cases in 2012**. Melanoma is one of themost serious consequences of skin cancer where melanocytesproliferate actively with enhanced accumulation of melaninpigment leading to hyperpigmentation and tumor formation. Up-regulated levels oftyrosinase enzyme appear to be correlated to with greater production and accumulation of melanin which induces skin cancer. Tyrosinase (EC 1.14.18.1) is an oxygen oxidoreductase enzyme involved in vertebrate cutaneous pigmentation, browning of fruits and vegetables, and morphogenesis and fruiting body formation in fungi.…

    • 603 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    She was thirty-four years old and 39 weeks pregnant when she was diagnosed with life threatening lung cancer. She and her husband decided to actively manage the tumor. They started chemo and kept changing drug after drug because it did not work. Another patient around eighty years old had end-stage respiratory and kidney failure. Her husband had died long ago with feeding tube and tracheostomy and she saw the pain he had undergone.…

    • 1336 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    Malignant mesothelioma is considered as an aggressive form of cancer and giving out accurate prognosis is not that easy. Prognosis for patients diagnosed with malignant mesothelioma is somehow discouraging since it has a long latency period. In most cases, it is only identified when it is in a radical stage already. What is malignant mesothelioma?…

    • 512 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Basal, squamous, and melanomas cell cancer are the 3 main skin cancers. As I said before the main cause of getting skin cancer is too much exposure of the sun's ultraviolet rays. The main areas of skin cancer is the scalp, face, lips, ears, neck, chest, arms and hands, and on legs of women but also you get it on unexposed areas of the skin as palms, beneath your fingernails or toenails, and genital area. Symptoms of basal cell carcinoma is pearly or waxy bumps, and flat, flesh-colored or brown scar like lesions. In squamous cell carcinoma the symptoms are firm, red nodule, and a flat lesion with scaly, crusted surface.…

    • 711 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. This research will be covering the functions, structures, layers, and diseases of the skin. The skin covers the entire external surface of the human body and serve a variety of purposes. It serves as a protective barrier that prevents internal tissues from exposure to trauma, UV, radiation, temperature extremes, toxins, and bacteria. The skin consists of three layers but the two main ones are the epidermis and the dermis.…

    • 1280 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    Malignant tumors rapidly spread throughout the body, attacking tissues and the surrounding regions. The only cure for this tumor…

    • 815 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Essay On Neoplasm

    • 465 Words
    • 2 Pages

    The term neoplasm refers to tumors that are masses or growths that arise from normal tissue. Can a growth occur at any time in life? Are all neoplasms life-threatening? Explain in your own words why or why not.…

    • 465 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Sansoucy was diagnosed with sarcoma, a cancer that develops in certain tissues like bone or muscle. Though rare in comparison to other cancers, approximately 4,870 adults and children (2,600 males and 2,270 females) were predicted to die from sarcoma this year. The five year survival rate (percentage of individuals who live at least five years after diagnosis) for this serious disease depends on the location of the tumors. Localized sarcomas are given an 83% five-year survival rate while regional stage sarcomas are given 43%, and sarcomas that have spread to distant body areas are given only a 16% five-year survival rate. (Cancer.…

    • 966 Words
    • 4 Pages
    Improved Essays