a. Mentorship Plans to Enhance her Technical Repertoire. Dr. Rizvi will work in my laboratory, acquiring technical expertise in a wide variety of experimental approaches including use of genetically engineered mouse models of CCA, and patient derived xenografts of CCA (PDX). She will also become adept at cell biology approaches including confocal microscopy coupled with computer-based 3-D image reconstruction, expression and use of fluorescence-based bioprobes, gene silencing and editing technology, immunofluorescence and immunohistochemical approaches, and culture of human CCA organoids. She will also become familiar and adept at pursuing biochemical and genetic techniques …show more content…
Within the Mayo Digestive Diseases Research Center (DK84567), we also have well established imaging and genetic cores which she will also avail herself to …show more content…
Mentorship to sharpen communication Skills. The communication skills necessary for a successful scientist include both oral and written skills. The written skills relate to abstract, manuscript, and grant writing all of which require different writing approaches. Dr. Dong and I will work closely with her on writing abstracts, manuscripts, and grant submissions. Dr. William Faubion will also review her grants in detail given his experience as a current member of a standing NIH study section. With direct mentorship from the three of us, she will be the beneficiary of constructive feedback to help ensure that she acquires and perfects her writing skills. In regards to oral communication skills, she will present research updates twice a year in our weekly seminar series within our DDRC (DK84567) enrichment series, rehearse all oral presentations for national meetings within this same format, and once a year she will give a campus wide seminar in the DDRC monthly seminar series. All members of her mentorship committee will be expected to be in attendance and provide constructive