Analysis Of The Origami Of Dna

In Today’s Science article titled The Origami of DNA it was about how Genome is organized in looping. Genetic material stored in the nucleus in a compressed way that let on amounts of data to be stored in bitty places. Society had very clear perspective on how genomes were stored until recent times. Researchers have found approach that helps find the grouping of the human genome in three dimensions. Researchers discovered much of the genome was package into loops. The loops transform into huge domains. The Method the Researchers perform shows genes that are distant for one another in the genome can be stored closely together this allows the genes to have similarly. Human genome contain huge numbers of genetic codes by DNA that grants a cell …show more content…
One for instead was “Enhancer”. Enhancers change how active genes are. Enhancer relates to the article by having an enhancer close to a different type of genes it can show whether the genes are active or silenced. Closeness relates to the folding and looping of DNA.Another word is “Chromatin Modification” The alteration of DNA which can determine how tightly genes can be stored. In Chromatin Modification DNA is surrounded by proteins called “Histones”. Histones was another word I didn’t know until I read this article. Histones have a positive charge. Therefor when DNA is near a Histones the two will most likely attracted. The stronger the histone is the tighter the DNA will be bounded. In the Article it also says histones can tune this association by tweaking pieces of the histones called histones tails. The Last word I didn’t understand was “Ligases”. Ligases put together DNA near other.DNA that are far for each other will not be stitched. DNA is distant from proteins and genome one area is close to another piece of DNA. Ligases has a lot to do with 3-D mapping and has a lot to do with DNA and …show more content…
The article had a lot to do with DNA and genes and how looping and folding of other.DNA allows cells to function correctly. Cells are basically a huge map for proteins and different things. In the Article shows how there were a lot of experiment taking place into the origami of DNA.Another Experiment that took place in the article was the HI-C method they found that there was 4.9 billion points in the genome in one segment. Looping were combine with histone that have been turn on by genes. At the same time the loops contained tiny parts where a protein is called CTCF.Researcher found large parts of gene looped together. There were a lot of experiments that took place in my article talking about looping and folding DNA.They also talk about Y chromosome and X chromosome with the 3-D experiment. Folding happen in cancer cells they can use 3-D maps to help find a cure. This is just some of the experiments they did in the article I