Loop Diuretic Research Paper

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Thiazide Diuretics are very similar to loop diuretics in that they both get rid of sodium, chloride, potassium and water. Thiazide diuretics work at the proximal part of the distal convoluted tubule. Thiazides have the ability to increase uric acid plasma and glucose plasma levels. The only big difference between thiazide diuretics and loop diuretics is that the amount of diuresis make by thiazides are very low compared to the biggest amount of diuresis created with loop diuretics. Sulfonamide is a drug class under thiazide diuretic and an important nursing considerations is to not give this diuretic to patients who are allergic to sulfa. Thiazide diuretics also are not that successful even when urine production is very little. Another big thing to note is that thiazide diuretics take longer time to work compared to loop diuretics. It peaks in about 4-6 hours and can be adminstered orally.

Hydrochlorothiazide is the most common thiazide used. It is often the first pick choice to treat hypertension. Edema and diabetes insipidus are other problems that hydrochlorothiazide can help
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These drugs include digoxin, hypertensive medications, Lithium, because of the sodium that is leaving the body with diuretics it can decrease the secretion of lithium. NSAIDs are also another drug that can affect the way the diuretics should work. The only difference from loop diuretic and thiazide diuretic is that thiazide diuretics can be used with ototoxic drugs without the risk of having hearing loss.

Other Thiazide drugs can include Chlorothiazide, methyclothiazide, chlorthalidone, indapamide, and metolazone. All of these drugs are taken only orally except for chlorothiazide. Chlorothiazide can be taken orally and IV (Burhttps://www.grammarly.com/?q=writing&utm_source=placement&utm_medium=cpc&utm_content=46860B.png&utm_term=paperraterchum & Rosenthal, 2016, p.

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