Lancet Infectious Diseases

Improved Essays
Please find enclosed our manuscript entitled “High Rates of Antibiotics Prescriptions for Outpatients with Acute Respiratory Tract Infections in Japan, 2013-2015: A Retrospective Cohort Study”, which we would like to submit for publication as an original research article in The Lancet Infectious Diseases. This manuscript consists of 20 text pages, 3 tables, 3 supplementary tables and 1 supplementary figure.

High rates of antibiotic prescription, especially broad-spectrum, accelerate selective pressure on microbials to acquire resistance. Traveling of resistant microbials makes the problem a global threat. To tackle the threat internationally, we should share usage status of antibiotics in each country, especially countries consuming large amounts of antibiotics like Japan.

To describe prevalence and rate of antibiotic prescriptions, we analyzed 8.65 million outpatient visits with acute upper respiratory tract infection (ARTI) to 101606
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These information is immediately clinically applicable for physicians and others treating such patients, and is useful for public health policy makers. As a premier journal covering the board field of infectious diseases, we believe that the Lancet Infectious Diseases is the perfect platform from which to share our results with the international medical community.

We certify that this manuscript is original, has not been previously published, is not under consideration for publication elsewhere, and will not be submitted elsewhere until we have received your final decision. All the authors have read the manuscript and have approved this submission to the Lancet Infectious Diseases. This study was supported by JSPS KAKENHI (16K08910). All authors report no conflict of interest to

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