Labetolol Case Study

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A. ELECTIVE 5 5% 8 8% B. EMERGENCY 5 5% 9 9%

TABLE 8: APGAR SCORE OF THE BABIES AT THE TIME OF DELIVERY
S.NO APGAR Score LABETOLOL NIFEDIPINE NO.OF CASES % OF CASES NO. OF CASES % OF CASES
1 10 30 60% 28 56%
2 6-8 11 22% 13 26%
3 4-6 2 4% 2 4%
4 2-4 3 6% 4 8%
5 2-0 4 8% 3 6%

DISCUSSION:
Labetolol is an effective drug in control of hypertension in pregnancy. A study by G.D Lamming and E.M Symonds on Labetolol proved that Labetolol is a useful drug in the treatment of PIH.
A study by A.El Qarmalwi proved that Labetolol is well tolerated. it proved that Labetolol gives more efficient control of BP, may have beneficial effect on renal functions with fewer side effects.
In the present study Labetolol gave good control of HTN while having fewer side effects and beneficial effect on renal function by decreasing proteinuria. A randomised double blind study of hemodynamic evaluation of patients taking Labetolol and Nifedipine with pre eclampsia by
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The study shows the highest incidence of preeclampsia in age group of 19-28 yrs. The maximum incidence is in primis at term gestation. Most common type of HTN is pre-eclampsia. In the present study efficacy of nifedipine and labetolol are compared. Labetolol gave good control of BP with single agent, when the dose was titrated appropriately, till the BP was controlled. The control of BP was consistent with labetolol, and also could be used for longer duration without any additional therapy. Whereas with nifedipine, control of BP was inconsistent and required additional medication for proper control of BP. The patients who were treated with Labetolol were found to have favourable cervix and had spontaneous vaginal deliveries resulting in less maternal morbidity. Nifedipine often resulted in complications like tachycardia and palpitations, while labetolol group had very few side effects. Both the drugs were found to be safe for the

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