Krabbe Disease
According to the National Institute of Neurological Disorders and Stroke, “Krabbe Disease is a rare, inherited degenerative disease” (NINDS.nih.gov). It is diagnosed when a presence of globoid cells are found. Those are cells with more than one nucleus. A nucleus is like the brain of the cell where all the action happens. This disease breaks down the coating of nerve fibers or axons, those are called Myelin Sheath. This disease also breaks down brain cells which are imperative for everyday functioning and intelligence. This causes impairment of motor and mental skills. Krabbe disease is caused by a lack of an essential enzyme that myelin needs for metabolism, or its own energy. This enzyme is called galactocerebrosidase. This disease primarily affects infants and children but has been seen in adolescents and adults (NINDS.nih.gov).
Currently there are no cures for Krabbe Disease, but there have been medical trials on infants that have received blood that came from the umbilical cord that showed a slowing of their symptoms and a slight prolongation of their life expectancy. However, most infants, with Krabbe disease diagnosis results in mortality. Adults that are diagnosed usually have milder symptoms and a greater life expectancy, though Krabbe disease is less common during this age. …show more content…
The Center of Disease Control, CDC, did not have any information regarding Krabbe Disease. The NINDS was easy to read, clearly formatted and easy to understand (NINDS.nih.gov). NINDS website is even equipped with a listening device that will read the text for you (NINDS.nih.gov). The NINDS website also includes organizations that support or give more information regarding Krabbe Disease. Those organizations share their physical address, phone number and websites
According to the National Institute of Neurological Disorders and Stroke, “Krabbe Disease is a rare, inherited degenerative disease” (NINDS.nih.gov). It is diagnosed when a presence of globoid cells are found. Those are cells with more than one nucleus. A nucleus is like the brain of the cell where all the action happens. This disease breaks down the coating of nerve fibers or axons, those are called Myelin Sheath. This disease also breaks down brain cells which are imperative for everyday functioning and intelligence. This causes impairment of motor and mental skills. Krabbe disease is caused by a lack of an essential enzyme that myelin needs for metabolism, or its own energy. This enzyme is called galactocerebrosidase. This disease primarily affects infants and children but has been seen in adolescents and adults (NINDS.nih.gov).
Currently there are no cures for Krabbe Disease, but there have been medical trials on infants that have received blood that came from the umbilical cord that showed a slowing of their symptoms and a slight prolongation of their life expectancy. However, most infants, with Krabbe disease diagnosis results in mortality. Adults that are diagnosed usually have milder symptoms and a greater life expectancy, though Krabbe disease is less common during this age. …show more content…
The Center of Disease Control, CDC, did not have any information regarding Krabbe Disease. The NINDS was easy to read, clearly formatted and easy to understand (NINDS.nih.gov). NINDS website is even equipped with a listening device that will read the text for you (NINDS.nih.gov). The NINDS website also includes organizations that support or give more information regarding Krabbe Disease. Those organizations share their physical address, phone number and websites