Juno Therapeutic Analysis

Improved Essays
Cancer is one of the leading medical enigmas that doctors face today. It is a devastating disease that claims the lives of far too many people worldwide each year. In fact, according to the Centers for Disease Control and Prevention, 14 million people worldwide discover each year that they have cancer, and out of these 14 million, approximately 8 million people die globally from cancer. There is no doubt regarding the fact that the race to find a cure for cancer is rapidly increasing in popularity. This is because the need for one is quite high. That is where immunotherapy treatment comes into play. Immunotherapy is a form of “therapy that harness[es] the power of a patient’s immune system to combat [his or her] disease” (CAR T-Cell Therapy). …show more content…
Juno Therapeutics, alone, raised approximately $304 million in the first 16 months of its existence by rapidly gaining support for this upcoming treatment possibility. This biotechnology company licenses experimental T-cell treatments at multiple hospitals and cancer research centers throughout the United States. In fact, this company “was among the largest stock market offerings in the history of the biotechnology industry” because of this newfound discovery that T cells can potentially be used to cure cancer (Regalado). That statement is a definite testament to the prospects in T-cell immunotherapy treatment and the overwhelming willingness to explore the possibilities it may offer. Juno Therapeutics, however, is not the only company taking root and attempting to get a footing in the adoptive cell therapy research. Over 30 other biotechnological companies have now initiated clinical tests or are in the process of planning them. The U.S. Food and Drug Administration has actually given Juno and the Novartis Company a “breakthrough designation” title for their immunological research. This means that their treatments for leukemia can be approved after only one larger clinical trial – making it easier to gain this approval while eliminating the gruesome red tape that most companies find themselves lodged within. (Regalado). This is a direct implication that this form of immunotherapy may actually become one of the fastest approvals for treatment in the history of medical biotechnology as MIT has

Related Documents

  • Improved Essays

    I am Kerry Matthews, who just got a new job at Oncoshrink Pharmaceutical Inc. as a new manager of the new clinical operation department. Oncoshrink is a new established pharmaceutical company in the recent year, which eager to extend the scale and bring new products to the market. Even through there are few products processes on the pipeline, the product lines in the future still seems optimistic, especially the Shrivelstain, a novel anti-cancer agent, which had done with phase I clinical trials and also brought significant benefits to the participants. The phase I clinical trials of Shrivelstain was managed by a CRO-ORMC (Oncology Research Management Corporation) and completed by BBMC (Best and Brightest Medical Center). Oncology Research Management…

    • 544 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The Benefits Of Melanoma

    • 818 Words
    • 4 Pages

    Melanoma is a type of cancer that is considered one among the most dangerous. Melanoma traces are usually found over the skin, but rarely it can even be found in the eye or even in the internal organs. The main cause of Melanoma is the direct exposure to the ultraviolent (UV) rays. Reducing tanning from sun or from tanning lamps can curtail the chance from Melanoma. For past decades, recovery from Melanoma was a nightmare.…

    • 818 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Jim Valvano Essay

    • 914 Words
    • 4 Pages

    Over the past twenty years, the Jimmy V foundation has raised more than $100 million. This speech is still relevant today because everyone knows someone who has suffered from this disease. “In the early recognition and treatment of cancer lies the hope of cure.” This is the motto of the American Society for the Control of Cancer, the national association composed of physicians and laymen whose object is the education of the public regarding the nature and treatment of this disease (Taussig). As much money as this country spends on war and technology, the fact there is still no cure for this disease baffles me.…

    • 914 Words
    • 4 Pages
    Improved Essays
  • Decent Essays

    Trastuzumab is a drug that was first discovered at UCLA’s Jonsson Comprehensive Cancer Center by scientists Dr. Axel Ullrich and Dr. H. Michael Shepard. UCLA along with Genentech, a biotechnology corporation, developed trastuzumab. The drug showed overall improvement in the survival rate of patients in the late stages of HER2-positive breast cancer. Together in 1992, UCLA and Genentech started the first clinical trial with 15 women and by 1996 the trial included over 900 women. Due to the drugs impressive results, advocates had pressured Genentech into working along side with the FDA to begin a lottery, which allowed women outside the trials to have access to the medication.…

    • 123 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    The most common side effect of colon cancer chemotherapeutic (CPT-11) is patients having severe diarrhea, caused by symbiotic bacterial β-glucuronidases. Which causes the drug to reactivate inside the gut. The enzymes were targeted without destroying bacteria that’s needed for human health. However, the purpose of these inhibitors is a way to prevent damage to mammalian cells that’s present in the intestines. If β-glucuronidase which causes the diarrhea isn’t inhibited the patients will have a higher risk of being infected and dehydrated.…

    • 806 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Treating Myeloma Analysis

    • 276 Words
    • 2 Pages

    Overall, this video explains the positive outcomes of using viruses, that once were considered deadly, to treat cancer. The documentary shows how ongoing research and trials of this kind of treatment is happening simultaneously in different places, and using different viruses. The first case mentions the study developed by Dr. Bell, who concluded that smallpox viruses can attack, and kill cancer cells without harming surrounding cells. Therefore, he and his team are working in treatment trials using vaccines containing genetically engineered smallpox viruses. On the other hand, Dr. Rusell came to a similar conclusion by treating myeloma, an extremely aggressive cancer, with a modified measles virus.…

    • 276 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Viruses have often seen as deadly particles of mass destruction. However, what if their ability to infiltrate cellular structures could be used for good rather than for evil? It seems that scientist in the field of medical virology have begun to explore such an option. One of the first viruses to be used in such manner is an engineered herpes virus, capable of provoking an immune response against cancer. Since this discovery the Food and Drug Administration (FDA) has approved a genetically engineered virus known as talimonogene laherparepvec, or T-VEC for short.…

    • 465 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    In 2012, two million deaths globally were caused by cancer; preventing those deaths could save many lives, including family and friends (World Health Organization). Although cancer does not personally affect everyone, cancer causes many controversies for family and friends. The effects of cancer impact many people’s lives, mainly friends and family of a patient with cancer. One way cancer affects family and friends is financially due to the cost of the treatments, hospitals, and bills that come along with having cancer. The treatments for cancer cost a lot of money; like chemo a few days of the week until the tumor is weakened.…

    • 676 Words
    • 3 Pages
    Improved Essays
  • Superior Essays

    I strongly believe that genetically modified cancer treatment through T-cell reprogramming can be exemplified as human beings taking the next step to beat cancer for good. It is a new way in which cancer can be eradicated from the human system, and it has proven to be better than chemotherapy, thus I’m in full support of this topic. Some of the terms in the topic may be clear and others may not. Genetic modification is related to the modification and manipulation of an organism to change its composition. This manipulation can be used to change organisms to become improved versions of themselves.…

    • 753 Words
    • 4 Pages
    Superior Essays
  • Great Essays

    Nanomedicine Essay

    • 1679 Words
    • 7 Pages

    When external antigen causes disease by infection, cell-mediated immune response in our body acts as basal defense system against exogenous pathogen. Native and adoptive immune system has established to attack infected cell by recognizing major histocompatibility complex (MHC). There are two major lymphocytes related to killing effect called cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells.[1], CTLs and NK cells recognize peptide epitope present on MHC class I to find infected cell. Especially, activated T cells are divided into effector T cell and memory T cell for effective defense system against secondary infection.[2] Cancer, which is classed as representative intractable disease, expresses TAA or mutated protein onto the surface of cancer cell.…

    • 1679 Words
    • 7 Pages
    Great Essays
  • Great Essays

    Cancer Immunotherapy: using immune based therapies to enhance the immune system to fight cancer cells. Introduction Cancer immunotherapy involves using components of the immune system to fight cancer cells. The immune system is very effective in getting rid of pathogens such as bacteria and viruses. The concept of unleashing the body’s ability to defend itself against cancer cells has long been a scientific discussion (Nathanson L. 1976). Over the last 10 years, scientists have synthesized drugs that block pathways to keep cancer cells into evading the immune system.…

    • 1172 Words
    • 5 Pages
    Great Essays
  • Improved Essays

    Although I quickly learned the ins and outs of stem cell research through many hours of practicing new techniques, I also realized the hardships that come along with research. I can vividly remember the first time I was able to show that knocking out an isoform of the Musashi gene led to fewer and smaller tumors on the intestines of mice, only after 5 months of work. I have always been intrigued by the ability of medicine to not only decrease mortality but also decrease morbidity through research. Recently, I have been testing new drug therapies in mice used as models of human cancers. To be involved in the translational science spectrum of medicine has further inspired me to pursue a career in medicine.…

    • 510 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Cancer Tumor Cell Therapy: Virus Versus Virus In a recent article published by Reuters, a group of researchers claims to have been able to genetically modify the mostly known cold-causing, adenovirus to attack cancer tumor cells, which is not new to the lot of cancer treatment as the US Food and Drug Association earlier approved the use of herpes virus to attack skin cancer cells. This kind of cancer cell therapy is not as impossible as it was curiously examined by scientists before since the genetic engineers, with the use of advances in gene modification, have developed progressive ways of manipulating certain viruses to attack tumor cells.…

    • 702 Words
    • 3 Pages
    Improved Essays
  • Superior Essays

    Essay On Heart Disease

    • 2836 Words
    • 12 Pages

    Cancer accounts for only half as many deaths. Because of the seriousness of this particular disease, people should be aware of the symptoms, and should also take preventative measures so that they are less susceptible to…

    • 2836 Words
    • 12 Pages
    Superior Essays
  • Improved Essays

    What is Gene therapy? Gene therapy is the process of supplementing or replacing a gene in order to treat a medical condition. This type of therapy allows the body to make the protein that is not being made by the missing or malfunctioning gene. Introduction of new genes through vectors overrides the malfunctioning gene and contributes to normal functioning of the body. The process begins when the modified DNA is inserted into a virus vector.…

    • 1019 Words
    • 5 Pages
    Improved Essays