Heterogeneity Of Cancer

Improved Essays
Invasive cancer is the cancer that spreads beyond the layer of tissue which developed and is growing into surrounding, healthy tissues. A lot of physicians try to detect and prevent the invasive cancers. Ductal carcinoma in situ is a non-invasive breast cancer. It does not spread beyond the milk duct into surrounding breast tissue. However, it can increase the risk of having invasive breast cancer later. Heterogeneity is a word that means diversity. It signifies the quality of state of being heterogeneous. Heterogeneity of cancer becomes important to treat and understand the cancer. Population bottleneck is a rapid reduction in the size of a population due to environmental events. Genetically diverse tumor has greater possibility to survive. …show more content…
A lot of physicians have been questioning how to treat and distinguish the precancerous cancers, non-invasive cancers, that could remain harmless or become invasive. Scientists try to understand by tracing cancer’s inherent heterogeneity. Cancer cells have unstable genomes that their chromosomes can gain or lose pieces with rapid speed, creating genetically diverse population. Now, researchers track the individual cancer cells more precisely which helps to know more about origins of cancer and how to improve treatments. Scientists find out that since pre-invasive cancer cells are highly unstable and potential to spread, those cells should be treated. With a genetically diverse tumor, there is a good chance that a few cells will survive when whole other cells die. With current technology, scientists are able to analyze the individual cancer cells in perspective of evolutionary biology which could help them pinpoint its cancer’s adaption and unlimited growth. When cancer cells reproduce, there is always a risk of error which DNA is mistakenly copied, chromosomes misalign, and break up into wrong cell. The new evolutionary approach, a phylogenetic tree, allows scientists to calculate which genes are more likely to be copied or die and become grow or survive. The tree approach is better to predict which primary tumors later metastasize. Other scientists are now starting to examine …show more content…
With the developed technology and the phylogenetic tree method, scientists are now able to investigate genes and cells individually to distinguish whether precancerous cells would become invasive cancer cells or not. Like general evolutionary biology notion, they find out cancer cells are also diverse genetically and more likely to survive in the changing environment. Some certain cancer cells may be empowered and adapt. So, they conclude even genetically diverse precancerous cells should be treated because they might hide their ability to spread. It was interesting that there is precancerous cells which does not spread around the body tissues but may become invasive. Also, it was surprising that the technology is so developed that scientists now can analyze every single cancer cell not average of them. Furthermore, just like other organisms, the more genetically diverse cancer cells, the higher chance to survive in changing environments. I would like to introduce this article to classmates because this article might be helpful to give some idea that how our current cancer research is improved and know about precancerous and cancer cell research. It will be long way to go; however, we are able to find treatment and cure the cancer completely

Related Documents

  • Improved Essays

    Henrietta Lacks Report

    • 596 Words
    • 3 Pages

    There two types of cancer invasive carcinomas and noninvasive. In 1941…

    • 596 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    What did cancer look like in the mid 1800’s http://www.cancer.org/acs/groups/cid/documents/webcontent/002048-pdf.pdf In 1838 german pathologist Johannes Muller showed cancer is made up of cells rather than lymph. Muller showed that cancer cells developed from budding elements (blastema) between normal tissues Rudolph Virchow suggested that cells including cancer cells are derived from other cells. He bliebed that cancer spread like liquid in the 1860s german surgeon karl theirch showed that cancer metasize through the spread of malignat . It introducd oncology into our perspective.…

    • 282 Words
    • 2 Pages
    Decent Essays
  • Improved Essays

    Lung Cancer Essay

    • 1525 Words
    • 7 Pages

    Lung Cancer Lung cancer is a malignant neoplasm of the lung tissue characterized by an uncontrolled cell proliferation. It is also referred to as carcinoma of the lung. This neoplasm arises from epithelia of the lungs, bronchi and trachea. Lung cancers can be of epithelial cell origin (carcinoma) or mesothelial cell origin (malignant mesothelioma). Lung cancer begins with inactivation of tumor suppressor genes or with activation of oncogenes.…

    • 1525 Words
    • 7 Pages
    Improved Essays
  • Improved Essays

    You have to check out bust cancer because how much time one can reside will depend on this level when bust cancer is actually identified. Ladies who are identified earlier using bust cancer get a better chance. Even for girls as their bust cancer haven't metastasized, his or her preventing possible opportunity to reside regarding a different 5 many years is all about 86%. Similar to cancer malignancy, bust cancer, develops inside stages. Big t, In, Mirielle along with 0-IV are typical strategies to categorize the different stages.…

    • 583 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Tumors are grouped either as benign or malignant. Benign tumor is not linked with cancer, and does not spread to other parts of the body. Benign tumors appear as one that stays at its origin of growth, because they do not show the rate (slow-growing rate) of how they develop new and different tissues. Moreover, benign tumors can sometimes lead to death although other normal begin tumors shows a sign of liberation, and how they are unable to cause harm. Yet, there are other types of benign growth like the skin tags which can be grouped as tumors, but they are not seen as abnormal growth of tissue.…

    • 236 Words
    • 1 Pages
    Improved Essays
  • Improved Essays

    1. Background:- Prognosis is the prediction of likely trail of the disease. It gives us perception on the natural history of a disease, apt cure strategies, patient management, decision making and most importantly information about the risk of death. Any clinical research has the aim to find the prognostic factors, which correlates genetic and clinical variables to the outcomes.…

    • 696 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Cancer is the name given to the disease in which changes in gene expression cause an uncontrollable division of abnormal cells in any given part of the body. Cell growth and division are regulated by specific genes, and these genes include those for growth factors, along with their receptors, and the intracellular molecules of signaling pathways. Cancer can occur whenever a mutation alters any of these genes. These mutations can be random and spontaneous, however they can also be caused by environmental factors such as chemicals, radiation, and X-rays. Oncogenes are mutated genes that play a role in transforming a normal cell into a cancerous tumor cell.…

    • 638 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Cancer is defined as a diverse state in which cells multiply, proliferate and spread through surrounding tissues. With all the different types of cancers we have, at least one originates from closely every cell type in the human body (Vogeistein and Kinzier,1992). Different influence can affect the processes of the cell cycle in both positive and negative ways. Tumor suppressor gene p53 is among the negative regulators of the cell cycle if affected by alteration, mutations or by interaction with oncogene products of DNA tumor viruses. All these mutations cause genetic changes in the cells and lead to cancer (Levine , Finlay, and Momand, 1991).…

    • 644 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Throughout history, human and animals have suffered from cancer. Despite the evolution of science and technology, cancer is still considered one of the deadliest diseases. In 2001, 48,100 deaths caused by colon cancer were estimated in the United States.(1) This made medical professionals aggressively seeka resolution to such a predicament. The treatment for any cancer differs from one individual to another.…

    • 678 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Cancer is the second most frequent cause of death in the world. Cancer is the uncontrolled growth of cells which can invade other parts of the body causing a neoplasm or tumor. Tumors can be either benign or malignant, with benign tumors usually remaining localized. (1) Continuous growth, prevention of programmed cell death, invasion of tissue, promotion of blood vessel constriction and formation of metastases are all characteristics of malignant tumors. Benign cancer does not present with symptoms while malignant cancers are more likely to be symptomatic with the appearance of a mass, prolonged cough, lump, bleeding, change in bowel movements and unexplained weight loss.…

    • 279 Words
    • 2 Pages
    Decent Essays
  • Superior Essays

    Hereditary Cancer Cancer is one of the most unknown subjects in the medical world. When it comes, why it comes, and how to effectively contain it is still being studied. Treatments have been available to lessen the cancer, or in some cases, take it away. The medical community has come so far in our knowledge of cancer. Splitting cancer into two specific groups of somatic cancer and hereditary cancer, researchers are getting more information.…

    • 1357 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    Personalized Medicine

    • 761 Words
    • 4 Pages

    The advent of personalized medicine is moving us from a traditional “one-size-fits-all” approach, based on broad population averages, to a more precise health care that is customized for each individual patient. The sequencing of the human genome has initiated a genomic era of personalized medicine. Knowledge of patients genomic, gained through high through-put next generation sequencing (NGS) is offering opportunities for biological insights and clinical diagnostics. Advances in this field have led to powerful new discoveries and treatments that are designed for specific characteristics of each individual. The main goal in personalized medicine is to use patient’s genetic information to provide more accurate diagnoses, safer drug prescriptions…

    • 761 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Malignant tumors rapidly spread throughout the body, attacking tissues and the surrounding regions. The only cure for this tumor…

    • 815 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    This is the first step of identification of inherited cancer. We are also able to see…

    • 346 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    In the world today cancer is a frequently conferred issue. From treating cancer, to curing it, to preventing it. Most people understand the basics of cancer but do not know anything about the molecular genetic side of it. Although there are many reasons for someone to develop cancer that is not linked to genetics, there are many reasons that are linked to genetics. Among woman in the United States ovarian caner is the fifth leading cause of cancer related deaths ("BRCA1 & BRCA2 ").…

    • 1079 Words
    • 5 Pages
    Improved Essays

Related Topics