In patients undergoing brain surgery for glioma resection, what is the risk of iatrogenic brain damage due to the surgery?
SYNOPSIS:
This meta-analysis included 90 studies published between 1990 to 2010 comprised of a total of 8,091 adult patients undergoing surgery for resection of supratentorial infiltrative gliomas. The study aimed to find out if intraoperative brain stimulation mapping (ISM) prior to resection of the glioma lowered the risk of neurologic damage seen with accidental removal of healthy brain tissue in the process of tumor resection. The study found that neurologic deficits post-surgery were seen in 3.4% of patients who were treated with ISM. In contrast, 8.2% of patients who underwent glioma resection