WHAT IS BREAST CANCER
Breast cancer is a disease in which breast cells growth abnormally .Breast cancer is a malignant tumor of breast tissue suspected by clinical finding like breast lump, breast thickening or skin change .Breast cancer is the microscopic structure of living organisms .A biopsy is determined the type of cancer present .Bilateral cancer is diagnosed when separate primary breast cancer present in each breast.
There are several stages of breast cancer;
Stage 0 is a non –invasive tumor
Stage 1 is a small locally invasive without lymph node involvement
Stage 2 is a medium size tumor
Stage 3 is advanced cancer with axillary node metastases
Stage 4 the cancer has metastasized to other part of the body
GENETICS
Explanation
Breast …show more content…
Genetic factors In addition to family history the following genetic factors can be responsible for breast cancer risk.
• Cancer suspect --- genes. Most inherited cases of breast cancer are affected due to two abnormal genes BRCA1 (Breast Cancer Gene One) and BRCA2 (Breast Cancer Gene Two).
BRCA1 and BRCA2 are present in everyone. BRCA genes are help to keep breast cells work properly and to repair the cell damage .When these genes do not function properly due to mutation in these genes are passed from one generation to another, the chances of breast cancer increases .Breast cancer susceptibility is a complex process in which multiple genes may involved .Breast cancer linked with abnormal BRCA1 and BRCA2 are developed in younger women .Women with BRCA1 and BRCA2 gene have great number of chances to develop ovarian ,pancreatic ,colon and melanoma .
Tools
Multiplex ligation-dependent probe amplification (MLPA) & MAPH is the most commonly used technique for the detection of BRCA1/2
Breast cancer is a disease in which breast cells growth abnormally .Breast cancer is a malignant tumor of breast tissue suspected by clinical finding like breast lump, breast thickening or skin change .Breast cancer is the microscopic structure of living organisms .A biopsy is determined the type of cancer present .Bilateral cancer is diagnosed when separate primary breast cancer present in each breast.
There are several stages of breast cancer;
Stage 0 is a non –invasive tumor
Stage 1 is a small locally invasive without lymph node involvement
Stage 2 is a medium size tumor
Stage 3 is advanced cancer with axillary node metastases
Stage 4 the cancer has metastasized to other part of the body
GENETICS
Explanation
Breast …show more content…
Genetic factors In addition to family history the following genetic factors can be responsible for breast cancer risk.
• Cancer suspect --- genes. Most inherited cases of breast cancer are affected due to two abnormal genes BRCA1 (Breast Cancer Gene One) and BRCA2 (Breast Cancer Gene Two).
BRCA1 and BRCA2 are present in everyone. BRCA genes are help to keep breast cells work properly and to repair the cell damage .When these genes do not function properly due to mutation in these genes are passed from one generation to another, the chances of breast cancer increases .Breast cancer susceptibility is a complex process in which multiple genes may involved .Breast cancer linked with abnormal BRCA1 and BRCA2 are developed in younger women .Women with BRCA1 and BRCA2 gene have great number of chances to develop ovarian ,pancreatic ,colon and melanoma .
Tools
Multiplex ligation-dependent probe amplification (MLPA) & MAPH is the most commonly used technique for the detection of BRCA1/2